2. Signaling Pathways
  3. Apoptosis
  4. Caspase
  5. Caspase Degrader

Caspase Degrader

Caspase Isoform Comparison

Caspase Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-181132
    dCASP1-55
    		Degrader
    dCASP1-55 is a cereblon-dependent caspase-1 (CASP1) PROTAC degrader. dCASP1-55 induces excessive NF-κB activation, apoptosis, and moderate S-phase arrest in leukemic cells. dCASP1-55 suppresses colony formation of leukemic cells. dCASP1-55 can be used for the research of cancer, such as myeloid malignancies and acute myeloid leukemia.