Acyltransferase
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Acyltransferase Related Products (203)
Related Products (203)
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Cholestanol stearate
0 ImagesCat. No.: HY-186296CAS No.: 59000-66-7Cholestanol stearate serves as a substrate for plasma lecithin:cholesterol acyltransferase (LCAT), with an esterification rate of approximately 70% that of cholesterol. Cholestanol stearate contains both hydrophilic and lipophilic groups, and its components are related to the structural substances of natural products. Cholestanol stearate can be used in studies related to cerebrotendinous xanthomatosis and familial lecithin:cholesterol acyltransferase deficiency.
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Purpactin C
0 ImagesCat. No.: HY-N14649CAS No.: 133806-61-8Purpactin C is a cholesterol acyltransferase (ACAT) inhibitor.
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Pactimibe sulfate (Standard)
0 ImagesCat. No.: HY-100401ARCAS No.: 608510-47-0Synonyms: CS-505 (Standard)Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity.
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Gypsetin
0 ImagesCat. No.: HY-N14715CAS No.: 155114-38-8Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC50 of 0.65 μM.
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ALCAT1-IN-1
0 ImagesCat. No.: HY-150179CAS No.: 2245767-05-7ALCAT1-IN-1 is an ALCAT1 inhibitor.ALCAT1-IN-1 can be used for the research of aging and age-related diseases.
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PF-06471553 (Standard)
0 ImagesCat. No.: HY-108339RCAS No.: 1808094-07-6PF-06471553 (Standard) is the analytical standard of PF-06471553 (HY-108339). This product is intended for research and analytical applications. PF-06471553 is a potent, selective and orally available monoacylglycerol acyltransferase 3 (MGAT3) inhibitor, with an IC50 of 92 nM.
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Purpactin A
0 ImagesCat. No.: HY-N9552CAS No.: 133806-59-4Purpactin A is a cholesterol acyltransferase (ACAT) inhibitor found in Pen. Purpurogenum FO-6.
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Roselipin 1A
0 ImagesCat. No.: HY-N14581CAS No.: 232258-17-2Roselipin 1A inhibits diacylglycerol acyltransferases (DGAT) of rat hepatic microcosm.
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TP-020 (Standard)
0 ImagesCat. No.: HY-101857RCAS No.: 1800025-30-2Synonyms: MGAT2-IN-1 (Standard)TP-020 (Standard) (MGAT2-IN-1 (Standard)) is the analytical standard of TP-020 (HY-101857). This product is intended for research and analytical applications. TP-020 (MGAT2-IN-1), a chemical probe, is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively.
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PF-06424439 (Standard)
0 ImagesCat. No.: HY-108341RCAS No.: 1469284-78-3PF-06424439 (Standard) is the analytical standard of PF-06424439 (HY-108341). This product is intended for research and analytical applications. PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.
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A 922500 (Standard)
0 ImagesSynonyms: DGAT-1 Inhibitor 4a (Standard)A 922500 (Standard) is the analytical standard of A 922500 (HY-10038). This product is intended for research and analytical applications. A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of 9 and 22 nM against human and mouse DGAT-1, respectively.
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Roselipin 1B
0 ImagesCat. No.: HY-N14584CAS No.: 232258-18-3Roselipin 1B inhibits diacylglycerol acyltransferases (DGAT) of rat hepatic microcosm.
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Triethylcholine iodide
0 ImagesCat. No.: HY-W127668CAS No.: 5957-17-5Triethylcholine iodide is a choline acetyltransferase inhibitor and a regulator of the acetylcholine synthesis pathway. Triethylcholine iodide inhibits acetylcholine synthesis in brain tissues and blocks neuromuscular and autonomic ganglionic transmission. Triethylcholine iodide exerts weak curare-like effects at extremely high concentrations. Triethylcholine iodide elevates the pentylenetetrazol seizure threshold, alters electroencephalogram patterns in Felis catus, but does not affect the maximal electroshock seizure threshold in Oryctolagus cuniculus. Triethylcholine iodide can be used in seizure-related research.
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Glisoprenin B
0 ImagesCat. No.: HY-N14573CAS No.: 144376-63-6Glisoprenin B is a cholesterol acyltransferase (ACAT) inhibitor.
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CMX410
0 ImagesCMX410 is an orally active and selective Mycobacterium tuberculosis Pks13 acyltransferase domain inhibitor and anti-bacterial agent. CMX410 reacts with the catalytic serine of the Pks13-AT domain to form a stable β-lactam ring, disables the enzyme’s active site, reduces trehalose monomycolate and trehalose dimycolate levels, triggers cell lysis, and reduces intracellular bacterial burden. CMX410 can be used for the research of tuberculosis.
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Roselipin 2A
0 ImagesCat. No.: HY-N14580CAS No.: 232258-26-3Roselipin 2A inhibits diacylglycerol acyltransferases (DGAT) of rat hepatic microcosm.
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Amidepsin B
0 ImagesCat. No.: HY-N14793CAS No.: 169181-29-7Amidepsin B is a diacylglycerol acyltransferase (DGAT) inhibitor.
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Amidepsin C
0 ImagesCat. No.: HY-N14794CAS No.: 169181-30-0Amidepsin C is a diacylglycerol acyltransferase (DGAT) inhibitor.
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Phenylpyropene B
0 ImagesCat. No.: HY-N14688CAS No.: 556013-83-3Phenylpyropene B can inhibit ACAT activity with IC50 of 12.8 μM.
