Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (4062)
Related Products (4062)
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α-Isopropylaminohexanophenone hydrochloride
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Esculentoside T
0 ImagesCat. No.: HY-N2206CAS No.: 1346652-41-2Esculentoside T is a natural product that can be found in soybeans.
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Capilliposide C
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1-[4-(Dimethylamino)phenyl]-2-[(phenylmethyl)amino]-1-propanone hydrochloride
![1-[4-(Dimethylamino)phenyl]-2-[(phenylmethyl)amino]-1-propanone hydrochloride](https://file.medchemexpress.com/product_pic/hy-168836.gif "Click to View 1-[4-(Dimethylamino)phenyl]-2-[(phenylmethyl)amino]-1-propanone hydrochloride Product Detail")
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Albatrelin A
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Arachidonic acid sulfonate sodium
0 ImagesCat. No.: HY-173534Synonyms: AA sulfonate sodiumArachidonic acid sulfonate (AA sulfonate) sodium is a derivative of Arachidonic acid (HY-109590) containing a sulfonate group.
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17-Hydroxy Capsaicin
0 ImagesCat. No.: HY-W741817CAS No.: 69173-71-317-Hydroxy Capsaicin is a natural product that can be found in chili.
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3,4,-Dihydro-5-methoxyl-6-methyl-2-phenyl-2H-1-benzopyran-7-ol
0 ImagesCat. No.: HY-N17641CAS No.: 55670-26-33,4-Dihydro-5-methoxyl-6-methyl-2-phenyl-2H-1-benzopyran-7-ol is a 2H-1-benzopyran derivative that can be found in the essential oil of Dalbergia pinnata (Lour.) Prain.
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Cicletanine hydrochloride
0 ImagesCat. No.: HY-W700616CAS No.: 82747-56-6Cicletanine hydrochloride is an orally active Furopyridine-derivative antihypertensive agent. Cicletanine hydrochloride stimulates NO release. Cicletanine hydrochloride induces effective pulmonary vasodilation.
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Curzeone
0 ImagesCat. No.: HY-N16789CAS No.: 104068-56-6Curzeone is a natural sesquiterpene.
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Tinosporol C
0 ImagesCat. No.: HY-N16921CAS No.: 2244777-14-6Tinosporol C is a natural diterpene.
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c-(2'FdAMP-2'FdIMP)
0 ImagesCat. No.: HY-112880CAS No.: 1951464-78-0c-(2'FdAMP-2'FdIMP) (Compound 52),a derivative of cAIMP (HY-134375), is a cyclic dinucleotide (CDN). c-(2'FdAMP-2'FdIMP) is a STING activator and significantly induce STING-dependent IRF and NF-κB pathway signaling. c-(2'FdAMP-2'FdIMP) can be used for STING-based immunotherapy, such as cancers and infectious diseases research.
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Quininone
0 ImagesCat. No.: HY-W743904CAS No.: 84-31-1Quininone is a Quinine (HY-D0143) derivative that exhibits in vitro antifungal activity. Quininone can be used for antifungal research.
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Procyanidin A3
0 ImagesCat. No.: HY-N4145CAS No.: 86631-39-2Synonyms: Cinnamtannin A3; Cinnamtannin IIProcyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy.
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Triumbelletin 7-O-glucoside
0 ImagesCat. No.: HY-N17063CAS No.: 2222584-03-2Triumbelletin 7-O-glucoside is a natural coumarin.
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Schisandroside A
0 ImagesCat. No.: HY-N8001CAS No.: 2059120-54-4Schisandroside A is a natural product that can be found in Schisandra chinensis?(Turcz.) Baill..
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Meliatoosenin K
0 ImagesCat. No.: HY-N18172CAS No.: 1314643-37-2Meliatoosenin K is a trichilinin-type limonoid found in the fruits of Melia toosendan.
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Cholyl-L-tyrosine
0 ImagesCat. No.: HY-176966CAS No.: 18485-51-3Synonyms: TyrCACholyl-L-tyrosine (TyrCA) is a cholyl conjugate of L-tyrosine (HY-N0473). Cholyl-L-tyrosine can be effectively hydrolyzed by pancreatic juice.
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1(S)-Tetrahydrocannabidiphorol
0 ImagesCat. No.: HY-172848A1(S)-Tetrahydrocannabidiphorol is a drug analogue and can be used for the research of neurological disease.
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Epicatechin-5-O-β-D-glucopyranoside
0 ImagesCat. No.: HY-N18278CAS No.: 131831-20-4Epicatechin-5-O-β-D-glucopyranoside (Compound 9) is a glucoside. Epicatechin-5-O-β-D-glucopyranoside forms via regioselective 5-O-β-D-glucosylation of epicatechin of quercetin 3-O-D-glucoside.
