Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
All Product Categories
-
Drug Derivative Inhibitors
(12)
View all products
-
Drug Derivative Agonist
(1)
View all products
-
Drug Derivative Activator
(1)
View all products
-
Drug Derivative Chemical
(1)
View all products
-
Drug Derivative Inducer
(1)
View all products
-
Drug Derivative Controls
(38)
View all products
-
Drug Derivative Substrate
(1)
View all products
-
Drug Derivative Related Products (4056)
Related Products (4056)
-
Avocadene
0 ImagesCat. No.: HY-W753557CAS No.: 24607-08-7Avocadene is a natural product isolated from Persea americana leaves, with anticancer, insecticidal, anti-Helicobacter pylori, and anti-inflammatory activity. Avocadene exerts antibacterial and anti‑inflammatory effects by suppressing Helicobacter pylori growth and inhibiting protein denaturation. Avocadene displays obvious cytotoxic activity against human prostate cancer PC‑3 cells with an IC50 of 0.5 μg/mL. Avocadene can be used for research of Helicobacter pylori‑associated gastrointestinal inflammation, gastroduodenal injury and prostate tumors.
-
9,10-Dihydrophenanthrene
0 ImagesCat. No.: HY-W016470CAS No.: 776-35-29,10-Dihydrophenanthrene is an analogue of 9,10-Phenanthrenequinone (HY-W014507). 9,10-Dihydrophenanthrene loses its anti-tumor activity that induces apoptosis in HCT-116 and HL-60 tumor cells.
-
Nisobamate
0 ImagesCat. No.: HY-U00204CAS No.: 25269-04-9Synonyms: W1015Nisobamate (W1015) is a tranquilizer.
-
Compound 2
0 ImagesCat. No.: HY-U00358CAS No.: 872313-42-3Compound 2 is an active compound used for the research of metabolic bone diseases.
-
AU-224
0 ImagesCat. No.: HY-U00020CAS No.: 287399-47-7AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects.
-
Pyridazinediones-derivative-1
0 ImagesCat. No.: HY-U00127CAS No.: 147493-44-5Pyridazinediones-derivative-1 has potential in treating neurodegenerative disorders. It shows an ED50 of 2.1 μM for inhibiting glutamate-induced contractions of isolated guineapig ileum.
-
Pyrrole-derivative1
0 ImagesCat. No.: HY-U00059CAS No.: 474006-30-9Pyrrole-derivative1 is extracted from patent WO/2002/085851A1, example 2, developed for the treatment of diabetic disease.
-
Hydrocarbon chain derivative 1
0 ImagesCat. No.: HY-U00332CAS No.: 300762-25-8Synonyms: 6,6'-Oxybis[2,2-dimethyl-1-hexanol]Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.
-
Antiasthmatic Compound 1
0 ImagesCat. No.: HY-U00409CAS No.: 63768-49-0Antiasthmatic Compound 1 is an antiasthmatic agent, which has the potential for allergic asthma treatment.
-
Glycerol derivative 1
0 ImagesCat. No.: HY-U00378CAS No.: 128400-55-5Glycerol derivative 1 is a Glycerol derivative extracted from patent EP 672415 A1, compound (1).
-
Deloxolone
0 ImagesCat. No.: HY-U00278CAS No.: 68635-50-7Synonyms: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)olean-9(11)-en-29-oic acidDeloxolone has the potential for inflammatory, ischemic and proliferative diseases treatment.
-
Anti-hypertensive sulfonanilide 1
0 ImagesCat. No.: HY-U00301CAS No.: 129280-22-4Anti-hypertensive sulfonanilide 1 is a potent antihypertensive agent extracted from patent EP0338793A2, compound XVIIIa,b*, example No.1.
-
Antiulcer Agent 1
0 ImagesCat. No.: HY-U00122CAS No.: 76001-09-7Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration at an exploratory stage of new agent development.
-
Carbazole derivative 1
0 ImagesCat. No.: HY-U00323CAS No.: 164914-28-7Synonyms: 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazoleCarbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.
-
Urinary Incontinence-Targeting Compound 1
0 ImagesCat. No.: HY-U00357CAS No.: 137315-05-0Urinary Incontinence-Targeting Compound 1 is a sulfonanilide derivative, used in the research of urinary incontinence.
-
Heterocyclyl carbamate derivative 1
0 ImagesCat. No.: HY-101831CAS No.: 168830-01-1Heterocyclyl carbamate derivative 1 is a heterocyclyl carbamate derivative that may be used for the research of inflammatory and neurological diseases.
