Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1268)
Related Products (1268)
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Stearic acid-PEG3400-Rhodamine
0 ImagesCat. No.: HY-W440935Stearic acid-PEG3400-Rhodamine is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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MeDZ lipid
0 ImagesCat. No.: HY-185284MeDZ lipid is a zwitterion-type ionizable endosomal membrane destabilizer and anti-inflammatory agent that promotes endosomal escape. When incorporated into LNP formulations, MeDZ lipid enhances mRNA expression in lymph node antigen-presenting cells and promotes cytotoxic T cell activation. MeDZ lipid is compatible with existing targeted nanoparticle formulations to improve mRNA delivery efficiency.
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Lipid M
0 ImagesCat. No.: HY-132289CAS No.: 2089251-57-8Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability.
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L-Arg-DSPE
0 ImagesCat. No.: HY-182988CAS No.: 2681258-65-9L-Arg-DSPE is an arginine-functionalized DSPE lipid containing free guanidine groups. L-Arg-DSPE serves as a component of NO-responsive degradable drug-loaded liposomal nanomotors (L-Arg@Lip-DOX), promoting drug deep tumor tissue penetration and cellular internalization. L-Arg-DSPE can be used for the research of drug delivery.
![3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol](https://file.medchemexpress.com/product_pic/hy-149664.gif "Click to View 3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol Product Detail")
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DSPE-PEG3400-Cy5
0 ImagesCat. No.: HY-W440912DSPE-PEG3400-Cy5 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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DSPE-PEG5000-Fluor 488
0 ImagesCat. No.: HY-160270DSPE-PEG5000-Fluor 488 is a PEG-dye-lipid conjugate consists of a DSPE phospholipid which is an unsaturated phospholipid, a Fluor 488 dye which is a cyanine dye that is prominently used in fluorescence microscopy with excitation and emission maxima at 499 nm and 520 nm and a large PEG spacer which links the former substance together.
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1,2-Dipalmitoyl-sn-glycero-3-PS
0 ImagesCat. No.: HY-145539ACAS No.: 40290-42-41,2-Dipalmitoyl-sn-glycero-3-PS is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS is used for the preparation of phospholipid bilayers.
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A-066
0 ImagesCat. No.: HY-185223CAS No.: 1192362-77-8A-066 (Formula I) is a cationic lipid. A-066 forms Cationic-Based Lipid Encapsulation Systems (CaBLES) or Lipid-Based Particles. A-066 facilitates delivery of nucleic acids and other agents.
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6-Bromohexyl 2-hexyldecanoate
0 ImagesCat. No.: HY-W440811CAS No.: 2644752-91-86-Bromohexyl 2-hexyldecanoate is a lipid. 6-Bromohexyl 2-hexyldecanoate can be used to build lipid nanoparticles and nanomaterials.
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DSPE-PEG3400-Cy3
0 ImagesCat. No.: HY-W440909DSPE-PEG3400-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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DOSPA (hydrochlorid)
0 ImagesCat. No.: HY-158867CAS No.: 913194-16-8DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
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nor-MC3
0 ImagesCat. No.: HY-185010CAS No.: 2870681-06-2nor-MC3 is an MC3-type ionizable lipid with C17 unsaturated chains, formulated in lipid nanoparticles for nucleic acid (mRNA and siRNA) delivery and supports in vitro and in vivo transfection.
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08:0 PG sodium
0 ImagesCat. No.: HY-157711CAS No.: 322647-21-208:0 PG sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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10A1P16
0 ImagesCat. No.: HY-185751CAS No.: 2760467-77-210A1P16 is an ionizable phospholipid composed of a tertiary amine, a phosphate group and three hydrophobic tails. As a spleen-selective RNA delivery vector, 10A1P16 successfully transfects approximately 30% of splenic macrophages and 6% of splenic B cells in vivo. 10A1P16 can be used to prepare spleen-selective 10A1P16-MDOA lipid nanoparticles, which effectively mediate mRNA delivery and gene editing in mouse models. This delivery system retains potent spleen-targeted mRNA delivery efficacy and can be applied to ovarian cancer research.
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18:0-20:4 PI (3,5) P2 triammonium
0 ImagesCat. No.: HY-157649CAS No.: 799268-58-918:0-20:4 PI (3,5) P2 triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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CL15H6
0 ImagesCat. No.: HY-173245CAS No.: 2256087-40-6CL15H6 is an ionizable lipid featuring biodegradable ester linkages and oleic acid lipid tails.
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IR-19-Py
0 ImagesCat. No.: HY-185759CAS No.: 2940240-84-4IR-19-Py is an ionizable lipid suitable for aerosolized mRNA delivery. When formulated into lipid nanoparticles, IR-19-Py delivers mRNA to nasal tissues in mice, achieving sustained nasal protein expression and dose-dependent pulmonary protein expression. IR-19-Py can be used in cystic fibrosis research.
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18:0 EPC chloride
0 ImagesCat. No.: HY-144019CAS No.: 328268-13-918:0 EPC chloride is a synthetic cationic phospholipid. 18:0 EPC chloride (at the critical synergistic concentrations of 2.34-2.93 μM) significantly improves the inactivation effect of eugenol against Escherichia coli.
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LNP Lipid-5
0 ImagesCat. No.: HY-153375CAS No.: 2430034-00-5LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP).
