2. Signaling Pathways
  3. Others
  4. Others
  5. Others Modulator

Others Modulator

Others Modulators (29):

Cat. No. Product Name Effect Purity
  • HY-120821
    Endosidin-2
    		Modulator 99.42%
    Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.
  • HY-124634
    PZ-2891
    		Modulator 99.38%
    PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.
  • HY-147149
    BPN-15477
    		Modulator 99.80%
    BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research.
  • HY-112103
    6-(γ,γ-Dimethylallylamino)purine
    		Modulator 99.87%
    6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.
  • HY-107661
    Arundic Acid
    		Modulator ≥98.0%
    Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid has the potential for stroke and Alzheimer’s disease research.
  • HY-112920
    TM-25659
    		Modulator 99.65%
    TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities.
  • HY-U00429
    NOT Receptor Modulator 1
    		Modulator 98.42%
    NOT Receptor Modulator 1 is a nuclear receptor NOT modulator extracted from patent WO 2008034974 A1, Example 39 in table1.
  • HY-135572
    TLX agonist 1
    		Modulator 99.94%
    TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity.
  • HY-153182
    GBT1118
    		Modulator 99.19%
    GBT1118 is a potent and orally active allosteric modifier of hemoglobin oxygen affinity. GBT1118 increases tolerance to severe hypoxia.
  • HY-133021
    Arazine
    		Modulator ≥98.0%
    Arazine (N-Acetyl-S-farnesyl-L-cysteine) is a cell-permeable modulator of G protein and G-protein coupled receptor signaling. Arazine can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site.
  • HY-134863
    A1AT modulator 2
    		Modulator 98.32%
    A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of ＞1.0 μM and an EC50 value of ＜0.4 μM. A1AT modulator 2 can be used for the research of infection and inflammation.
  • HY-112101
    Prohydrojasmon racemate
    		Modulator ≥98.0%
    Prohydrojasmon racemate (n-Propyl dihydrojasmonate) is the racemate of Prohydrojasmon. Prohydrojasmon is a synthesized plant growth regulator.
  • HY-W008769
    Ethychlozate
    		Modulator
    Ethychlozate is a plant growth regulator on the promotion of flowering in citrus.
  • HY-156645
    Tegomil fumarate
    		Modulator
    Tegomil fumarate is an immunomodulator.
  • HY-P4812
    Prepro-von Willebrand factor (641-650) (bovine)
    		Modulator
    Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen.
  • HY-139564
    DOTA Zoledronate
    		Modulator
    DOTA Zoledronate is a next-generation agent for bone targeted radionuclide therapy for diagnosing bone metastases.
  • HY-P4708
    Excitin 1
    		Modulator
    Excitin 1 is an orally active and CNS-penetrated peptide, alters behavior and brain monoamine and amino acid concentrations in rats.
  • HY-P4813
    Preptin (rat)
    		Modulator
    Preptin, an osteogenic peptide product of the pancreatic beta-cell, corresponds to Asp69-Leu102 of pro-IGF-II.
  • HY-157999
    SDI-118
    		Modulator
    SDI-118 is an orally active modulator for synaptic vesicle glycoprotein 2A (SV2A) with an IC50 of 13 nM.
  • HY-153805
    Z-NCTS
    		Modulator
    Z-NCTS is an RNA mismatch binding molecule that recognizes the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence (X=U or A) and acts as a molecular glue for RNA.