Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2548)
Related Products (2548)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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TachypleginA
0 ImagesCat. No.: HY-114909CAS No.: 331839-29-3TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1，thereby causing a decrease in the activity of the parasite's myosin motor.
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Antiparasitic agent-28
0 ImagesCat. No.: HY-175648Antiparasitic agent-28 is an orally active, selective inhibitor of Toxoplasma gondii phenylalanine tRNA synthetase (TgcPheRS) with blood-brain barrier penetration. Antiparasitic agent-28 inhibits the growth of T. gondii tachyzoites (TgME49-Fluc strain) an (EC50 = 1 nM) and T. gondii bradyzoites (Tg68nLuc strain) induced by alkaline (EC50 = 3 nM) and glutamine-rich medium (EC50 = 0.1 nM). Antiparasitic agent-28 demonstrates potent anti-toxoplasmosis efficacy in mice infected with TgME49-Fluc tachyzoites. Antiparasitic agent-28 can be used for the study of Toxoplasma gondii infection.
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16-Deethylindanomycin
0 ImagesCat. No.: HY-N12178CAS No.: 106803-22-9Synonyms: A 83094A; Omomycin16-Deethylindanomycin (A 83094A) is an antibiotic, which can be produced by Streptomyces setonii. 16-Deethylindanomycin exhibits antimicrobial activities against gram-positive bacteria Staphylococcus spp. and Streptococcus with MIC of 2-4 µg/mL. 16-Deethylindanomycin exhibits anticoccidial activity against Eimeria tenella.
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C3361
0 ImagesCat. No.: HY-17656CAS No.: 91042-00-1C3361 is a moderate specific Plasmodium falciparum hexose transporter 1 (PfHT1) and Plasmodium berghei hexose transporter 1 (PbHT1) inhibitor with Ki values of 8.6 and 9.4 μM. C3361 inhibits TgGT1 with a Ki of 82 μM. C3361 attenuates hepatic (IC50 = 15 μM) and ookinete development of P. berghei. C3361 can suppress the growth of blood-stage parasites. C3361 can be used for the research of infection, such as malaria.
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Tigolaner (Standard)
0 ImagesCat. No.: HY-109077RCAS No.: 1621436-41-6Synonyms: BAY-1272858 (Standard)
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Sesquicillin A
0 ImagesCat. No.: HY-137801CAS No.: 51103-58-3Sesquicillin A is an insecticidal antibiotic, a fungal metabolite isolated from white plantain. Sesquicillin A inhibits the growth of A. salina brine shrimp with the MIC value of 6.25 µg/mL.
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TRPMPZQ-IN-1
0 ImagesCat. No.: HY-175507TRPMPZQ-IN-1 (Compound 52) is a TRPMPZQ inhibitor, with an EC50 of 0.38 μM against TRPMPZQ from Spirometra erinaceieuropaei. TRPMPZQ-IN-1 exhibits antiparasitic activity, showing an EC50 of 4.3 μM against Echinococcus multilocularis. TRPMPZQ-IN-1 can be used in antiparasitic research.
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Toltrazuril sulfone (Standard)
0 ImagesSynonyms: Ponazuril (Standard)Toltrazuril (sulfone) (Standard) is the analytical standard of Toltrazuril (sulfone). This product is intended for research and analytical applications. Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry.
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Antileishmanial agent-28
0 ImagesCat. No.: HY-138812CAS No.: 1135272-09-1Antileishmanial agent-28 (Compd 12) is an antileishmanial agent, with EC50 values of 1.5 μM (L.donovani), 13 μM (L.amazonensis) and 18 μM (J774A.1), respectively.
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Insecticidal agent 26
0 ImagesCat. No.: HY-178040Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC50 of 11.0 μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs).
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BL-1005
0 ImagesCat. No.: HY-179116Synonyms: BS2463BL-1005 (BS2463), thiophen-2-yl pyrimidine (TTP), is a potent paralytic of Schistosoma mansoni with an EC50 of 37 nM. BL-1005 shows low cytotoxicity for HEK293, HeLa and HepG2 cell with CC50 >20 μM. BL-1005 can induce paralysis in both adult and juvenile S. mansoni. BL-1005 can be used for the research of infection.
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Amodiaquine (Standard)
0 ImagesSynonyms: Amodiaquin (Standard)Amodiaquine (Standard) is the analytical standard of Amodiaquine. This product is intended for research and analytical applications. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
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Cyenopyrafen
0 ImagesCat. No.: HY-W719544CAS No.: 560121-52-0Cyenopyrafen is a mitochondrial complex II inhibitor and acaricide. Cyenopyrafen controls spider mites on fruit trees, vegetables and flowers.
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Azlocillin sodium salt (Standard)
0 ImagesSynonyms: Sodium azlocillin (Standard)Azlocillin (sodium salt) (Standard) is the analytical standard of Azlocillin (sodium salt). This product is intended for research and analytical applications. Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum.
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Antimalarial agent 46
0 ImagesCat. No.: HY-159900CAS No.: 2715225-19-5Antimalarial agent 46 (Compound 42a) is an antimalarial agent with antimalarial activity. Antimalarial agent 46 shows inhibitory activity against P. falciparum lines.
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ACT-451840 (Standard)
0 ImagesCat. No.: HY-111817RCAS No.: 1984890-99-4ACT-451840 (Standard) is the analytical standard of ACT-451840 (HY-111817). This product is intended for research and analytical applications. ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial.
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Spinosyn D aglycone
0 ImagesCat. No.: HY-137970CAS No.: 149439-79-2Synonyms: A-83543D aglyconeSpinosyn D aglycone is an aglycone form of the insecticide Spinosyn D (HY-125326). Unlike spinosyn D, spinosyn D aglycone is not lethal to H. virescens (tobacco budworm) neonate larvae (LC50=>64 ppm).
