NEU-5123
NEU-5123 is a human kinase inhibitor with potent inhibitory activity to several kinases. NEU-5123 is a Trypanosome proliferation inhibitor. NEU-5123 can be used for the research of infection.
For research use only. We do not sell to patients.
- Formula: C22H23N5
- Molecular Weight:357.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
NEU-5123 (Compound 18a) potently inhibits Trypanosoma brucei proliferation (PEC50 = 7.7), exhibits low toxicity to human lung fibroblast MRC5 cells (PTC50 = 4.8) with a SI of 850[1].
NEU-5123 (5 μM) potently inhibits 14 human kinases (defined as >50% inhibition) in a panel of 45 human kinases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 357.45
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Formula C22H23N5
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SMILES
CN1C=C(C=N1)C2=C3C=C(NC3=NC=C2)C4=CC=C(C=C4)CN5CCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NEU-5123 Related Classifications
HY-178326 Related Classifications
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