2. Signaling Pathways
  3. JAK/STAT Signaling
  4. Pim
  5. Pim Degrader

Pim Degrader

Pim Isoform Comparison

Pim Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-186146
    SGI-1776-VHL-02
    		Degrader
    SGI-1776-VHL-02 is a stereoselective PIM PROTAC degrader. SGI-1776-VHL-02 promotes the ubiquitination and degradation of PIM1, PIM2 and PIM3. SGI-1776-VHL-02 downregulates c-myc protein levels, induces Apoptosis. SGI-1776-VHL-02 has anti-cancer activity against prostate cancer. SGI-1776-VHL-02 can be used in studies related to prostate cancer.