Prostaglandin Receptor
Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors. There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors. These receptors are named: DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor. The prostaglandins are a group of hormone-like lipid compounds that are derived enzymatically from fatty acids and have important functions in the animalbody. There are currently ten known prostaglandin receptors on various cell types.
Prostaglandin Receptor Isoform Specific Products
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Prostaglandin Receptor Inhibitors
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Prostaglandin Receptor Agonists
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Prostaglandin Receptor Antagonists
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Prostaglandin Receptor Activators
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Prostaglandin Receptor Modulators
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Prostaglandin Receptor Inducers
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Prostaglandin Receptor Degrader
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Prostaglandin Receptor Controls
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Prostaglandin Receptor Ligands
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Prostaglandin Receptor Related Products (766)
Related Products (766)
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Antibodies (2)
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Prostaglandin Receptor Isoform Comparison
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L-644698
0 ImagesCat. No.: HY-122147CAS No.: 72313-41-8L-644698 is a potent and selective human recombinant prostaglandin D2 (PGD2) receptor (hDP) agonist with Ki values of 0.9, 267, 3730, 9280 nM for hDP, hEP2, hEP3, hEP4, respectively. L-644698 induces cyclic AMP production with an EC50 value of 0.5 nM.
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MK-447
0 ImagesCat. No.: HY-100297CAS No.: 58456-91-0MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
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15-keto-17-phenyl trinor Prostaglandin F2α
0 ImagesCat. No.: HY-113778CAS No.: 949564-89-0Synonyms: 15-keto-17-phenyl trinor PGF2α15-keto-17-phenyl trinor Prostaglandin F2α (15-keto-17-phenyl trinor PGF2α) is an F-series prostaglandin (PG) analog. The potential metabolite of 15-keto-17-phenyl trinor Prostaglandin F2α in animals is 15-keto PG. 15-keto PG can slightly reduce the intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto-17-phenyl trinor Prostaglandin F2α is a miotic agent in cats, reducing the pupil diameter by 8 mm at a dose of 5 μg/eye.
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ASP7657 free base
0 ImagesASP7657 free base is an orally active EP4 receptor antagonist, with Kis of 2.21 and 6.02 nM for the human and rat EP4 receptors.
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Nocloprost
0 ImagesCat. No.: HY-106054CAS No.: 79360-43-3Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist. Nocloprost inhibits evoked [3H]ACh release. Nocloprost has gastroprotective and ulcer-healing properties. Nocloprost accelerates the healing of chronic gastric ulcerations and enhances mucosal growth in rats.
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(S)-Trimetoquinol hydrochloride
0 ImagesCat. No.: HY-108282CAS No.: 18559-59-6Synonyms: (S)-AQL 208 hydrochloride; (S)-TMQ hydrochloride(S)-Trimetoquinol hydrochloride (Compound 1) is a apotent, nonselective, nonclassical β-adrenergic agonist and nonprostanoid thromboxane A2/prostaglandin H2 antagonist. (S)-Trimetoquinol hydrochloride can be used for research of neurological and cardiovascular disease.
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EP4 receptor agonist 3
0 ImagesCat. No.: HY-172099CAS No.: 634193-29-6EP4 receptor agonist 3 is an EP4 receptor agonist that can be used in the study of colitis models in mice with DSS.
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CGS-22652
0 ImagesCat. No.: HY-19132CAS No.: 134235-78-2CGS 22652 is a potent thromboxane A2 receptor antagonist. CGS 22652 has selective thromboxane A2 synthase inhibitory properties. CGS 22652 can be used in the research of coronary artery thrombosis.
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17-Phenyl trinor prostaglandin E2 ethyl amide
0 ImagesCat. No.: HY-138868CAS No.: 1219032-20-8Synonyms: 17-Phenyl trinor PGE2 ethyl amide17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis.
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6β-Prostaglandin I1
0 ImagesCat. No.: HY-130522CAS No.: 62770-50-7Synonyms: 6β-PGI16β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection).
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UK 34787
0 ImagesCat. No.: HY-123293CAS No.: 72818-36-1UK 34787 is a selective thromboxane synthetase inhibitor with little or no activity against cyclooygenase or prostacyclin synthetase.
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Wy 27569
0 ImagesCat. No.: HY-105866CAS No.: 103417-69-2Wy 27569 is an orally active vascular selective calcium channel blocker that can effectively lower blood pressure. Wy 27569 is a thromboxane synthase inhibitor that can reshape prostaglandin balance, reduce pro thrombotic TXA2, and increase anti thrombotic PGI2. Wy 27569 can be used for research on cardiovascular diseases such as hypertension and angina.
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Travoprost (Standard)
0 ImagesSynonyms: Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension.
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Nafagrel hydrochloride
0 ImagesCat. No.: HY-106111ACAS No.: 97901-22-9Nafagrel hydrochloride is a thromboxane A2 synthetase inhibitor. Nafagrel hydrochloride can prevent the accumulation of thrombus material in a rat model of acute arterial thrombosis.
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I-SAP
0 ImagesCat. No.: HY-118044CAS No.: 133538-58-6I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC).
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AH22921
0 ImagesCat. No.: HY-115827CAS No.: 74480-23-2AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.
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N-Cyclopropyl bimatoprost
0 ImagesCat. No.: HY-124241CAS No.: 1138395-12-6N-Cyclopropyl bimatoprost (Formula II), a prostaglandin analog, can be used in the study of epithelial-related conditions.
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15β-Travoprost
0 ImagesCat. No.: HY-139386CAS No.: 1420791-14-5Synonyms: 15(S)-Flu-Ipr15β-Travoprost (15(S)-Flu-Ipr) is an enantiomer of Travoprost (HY-B0584). Travoprost, an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist.
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Ricinoleic acid (Standard)
0 ImagesCat. No.: HY-N6070ARCAS No.: 141-22-0Ricinoleic acid (Standard) is the analytical standard of Ricinoleic acid. This product is intended for research and analytical applications. Ricinoleic acid, a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties.
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Prostaglandin D2 serinol amide
0 ImagesCat. No.: HY-137483CAS No.: 851761-42-7Prostaglandin D2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol.
