1. Signaling Pathways
  2. TGF-beta/Smad
  3. TGF-β Receptor
  4. ALK4 Isoform
  5. ALK4 Inhibitor

ALK4 Inhibitor

ALK4 Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-10431
    SB-431542
    Inhibitor 99.89%
    SB-431542 is a TGF-β receptor kinase inhibitor (TRKI).
  • HY-10432
    A 83-01
    Inhibitor 98.83%
    A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.
  • HY-10432A
    A 83-01 sodium
    Inhibitor
    A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.
  • HY-15897
    LDN-212854
    Inhibitor 99.70%
    LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC50: 1.3 nM).
  • HY-122856
    AZ12601011
    Inhibitor 99.88%
    AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM.
  • HY-10431G
    SB-431542 (GMP)
    Inhibitor
    SB-431542 (GMP) is SB-431542 (HY-10431) produced by using GMP guidelines.
  • HY-123900
    AZ12799734
    Inhibitor
    AZ12799734 is a selective, orally active TGFBR1 kinase inhibitor with an IC50 of 47 nM.