2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P992372
    huAA98
    huAA98 is a humanized monoclonal antibody and also a CD146 inhibitor. huAA98 binds to human CD146, regulates its activity and inhibits cancer-related angiogenesis, as well as tube formation, motility, proliferation and migration of endothelial cells. huAA98 inhibits angiogenesis in the chick chorioallantoic membrane assay and reduces microvessel density in human tumor xenograft models. huAA98 shows immunoreactivity only to neovascular vessels within tumors and inhibits the growth of tumor xenograft models. huAA98 can be used in studies related to cancer-related angiogenesis, liver cancer, leiomyosarcoma and pancreatic cancer.
    huAA98
  • HY-N16823
    Mulberroside E
    Mulberroside E is a natural phenolic compound.
    Mulberroside E
  • HY-N7566
    Jatamanvaltrate B
    Jatamanvaltrate B is a natural iridoid.
    Jatamanvaltrate B
  • HY-N17105
    Obacunone 17-O-glucoside
    Obacunone 17-O-glucoside is a natural triterpene.
    Obacunone 17-O-glucoside
  • HY-N17981
    (-)-Isorhamnetin 3-O-robinobioside
    (-)-Isorhamnetin 3-O-robinobioside (compound 6) is a flavonol glycoside. (-)-Isorhamnetin 3-O-robinobioside can be found in the aerial parts of Anthyllis sericea (Leguminosae).
    (-)-Isorhamnetin 3-O-robinobioside
  • HY-N17512
    Matairesinol-4'-O-glucoside
    Matairesinol-4'-O-glucoside is a natural product that can be found in podocarpus macrophyllus.
    Matairesinol-4'-O-glucoside
  • HY-N3650
    Curlignan
    Curlignan is a natural lignan.
    Curlignan
  • HY-182780
    LSPN925
    LSPN925 is an anticancer agent. LSPN925 exhibits cytotoxic and antiproliferative activities against tumor cells. LSPN925 has predicted oral bioavailability, low risks of hepatotoxicity and acute toxicity, and no risk of cardiotoxicity. LSPN925 can be used for the research of ovarian cancer, melanoma and breast cancer.
    LSPN925
  • HY-106748
    Nictiazem
    Nictiazem is a 1,5-benzothiazepine derivative. Nictiazem exhibits antidepressant activity and can be used in the research of neurological diseases such as depression.
    Nictiazem
  • HY-N13776
    Adenostemmoside A
    Adenostemmoside A is a natural diterpene.
    Adenostemmoside A
  • HY-113755
    AA-1777
    AA-1777 is an active compound.
    AA-1777
  • HY-N16935
    Queretaroic acid 28-O-glucoside
    Queretaroic acid 28-O-glucoside is a natural triterpene.
    Queretaroic acid 28-O-glucoside
  • HY-N17103
    5α,6α-Epoxy-3β-hydroxymegastigm-7-en-9-one
    5α,6α-Epoxy-3β-hydroxymegastigm-7-en-9-one is a natural sesquiterpene.
    5α,6α-Epoxy-3β-hydroxymegastigm-7-en-9-one
  • HY-158004
    SMU101
    SMU101 is an active compound.
    SMU101
  • HY-W980364
    Tridecan-4-ol
    Tridecan-4-ol is an alcohol compound that can be extracted from Rubia cordifolia L.
    Tridecan-4-ol
  • HY-N13765
    10-Dehydrogingerdione
    10-Dehydrogingerdione is a natural phenolic compound.
    10-Dehydrogingerdione
  • HY-N9037
    Drechslerine D
    Drechslerine D is a natural sesquiterpene.
    Drechslerine D
  • HY-180354
    Mopidralazine hydrochloride
    Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. Mopidralazine hydrochloride significantly reduces systolic blood pressure (ED50 = 1.94 mg/kg) in spontaneously hypertensive rats models. Mopidralazine hydrochloride has a slower onset of action but a longer duration of action and has a significantly smaller effect on increasing heart rate in canine model of renal hypertension. Mopidralazine hydrochloride can be used for the research of hypertension.
    Mopidralazine hydrochloride
  • HY-126635A
    Mafoprazine methanesulfonate
    Mafoprazine methanesulfonate is a phenylpiperazine derivative with variable affinities for neuronal receptors. It may exert its antipsychotic effects primarily through D2 receptor blockade and α-adrenergic activity, and may increase the activity of dopamine metabolites.
    Mafoprazine methanesulfonate
  • HY-114198
    Tenovin-2
    Tenovin-2 is an active compound.
    Tenovin-2