2. Signaling Pathways
  3. Immunology/Inflammation
  4. E-Selectin
  5. E-Selectin Antagonist

E-Selectin Antagonist

E-Selectin Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-125475
    Rivipansel
    		Antagonist
    Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin. Rivipansel binds tightly to the lectin domain of E-selectin, and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin. Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease.