FASTK Modulator
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Rhinacanthin C
0 ImagesCat. No.: HY-N15205CAS No.: 159278-74-7Rhinacanthin C is an orally active naphthoquinone ester and P-gp inhibitor (IC50 = 5.20 μM). Rhinacanthin C exerts effects in ameliorating hepatic steatosis, insulin resistance, and inflammation by inhibiting P-gp, BCRP, OATP1B1/1B3, and multiple CYP enzymes, downregulating lipid synthesis-related factors such as ACC and FAS, and upregulating AMPKα phosphorylation and SIRT1. Rhinacanthin C can be used in research on non-alcoholic fatty liver disease, diabetes, abnormal osteolysis, Alzheimer's disease, and inflammation.
