Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
All Product Categories
-
Isotope-Labeled Compounds Related Products (11100)
Related Products (11100)
-
9(S)-HODE-d4
0 ImagesSynonyms: Alpha-dimorphecolic acid-d49(S)-HODE-d4 (Alpha-dimorphecolic acid-d4) is the deuterium labeled 9(S)-HODE (HY-113455). 9(S)-HODE (Alpha-dimorphecolic acid) is the major active derivative of Linoleic acid (HY-N0729). 9(S)-HODE regulates the expression of miR-361-3p. 9(S)-HODE reduces cancer cell viability and induces cancer cell apoptosis. 9(S)-HODE can be used in the research of acute myeloid leukemia.
-
Oclacitinib-13C-d3
0 ImagesOclacitinib-13C-d3 is the deuterium and 13C labeled Oclacitinib.
-
4-Fluorobenzaldehyde-2,3,5,6-d4
0 ImagesSynonyms: 4-Fluorobenzaldehyde--d44-Fluorobenzaldehyde-2,3,5,6-d4 is the deuterium labeled 4-Fluorobenzaldehyde-2,3,5,6-d4.
-
L-Ascorbic acid-13C6-1
0 ImagesSynonyms: L-Ascorbate-1; Vitamin C-13C6-1L-Ascorbic acid-13C6-1 (L-Ascorbate-1; Vitamin C-13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
-
γ-Tocopherol-d4
0 Imagesγ-Tocopherol-d4 is the deuterium labeled γ-Tocopherol. γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity.
-
3-Hydroxykynurenine-13C3,15N
0 ImagesCat. No.: HY-113294SCAS No.: 2267306-16-9Synonyms: 3-Hydroxy-DL-kynurenine-13C3,15N3-Hydroxykynurenine-13C3,15N (3-Hydroxy-DL-kynurenine-13C3,15N) is the 13C and 15N labeled 3-Hydroxykynurenine (HY-113294). 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis.
-
4-Hydroxypropranolol-d7 hydrochloride
0 ImagesSynonyms: (±)-4-Hydroxy Propranolol-d7 hydrochloride4-Hydroxypropranolol-d7 (hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties.
-
Semicarbazide-13C,15N2 hydrochloride
0 ImagesSynonyms: Aminourea-13C,15N2 hydrochloride; Hydrazinecarboxamide-13C,15N2 hydrochlorideSemicarbazide-13C,15N2 (Aminourea-13C,15N2) hydrochloride is the 13C- and 15N-labeled Semicarbazide hydrochloride (HY-Y0470). Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles.
-
C18 Glucosyl(ß) ceramide-d5
0 ImagesC18 Glucosyl(ß) ceramide-d5 is deuterium labeled C18 Glucosyl(ß) ceramide.
-
SADDNIKTPAE(Arg-13C6,15N4)LLGPLPPSADDNLKT TFA
0 ImagesCat. No.: HY-159192SSADDNIKTPAE(Arg-13C6,15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA).
-
Boscalid-d4
0 ImagesCat. No.: HY-119976SCAS No.: 2468796-76-9Boscalid-d4 is the deuterium labeled Boscalid. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis.
-
13(S)-HODE-d4
0 ImagesCat. No.: HY-123007SCAS No.: 139408-39-213(S)-HODE-d4 is the deuterium labeled 13(S)-HODE.
-
Rosiglitazone-d4
0 ImagesCat. No.: HY-17386S1CAS No.: 1132641-21-4Synonyms: BRL 49653-d4Rosiglitazone-d4 is deuterated labeled Rosiglitazone (HY-17386). Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone is an TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone can be used in the research of obesity and diabetes, senescence, ovarian cancer.
-
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester-d3
0 ImagesCat. No.: HY-W249514CAS No.: 1022151-50-31-Methyl-1H-pyrazole-4-boronic acid pinacol ester-d3 is the deuterium labeled 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester (HY-I0308). 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
-
Glycyl-L-proline-15N,d2 trifluoroacetate
0 ImagesCat. No.: HY-144250SPurity: 98.86%Glycyl-L-proline-15N,d2 (trifluoroacetate) is a 15N-labeled and deuterium labeled Glycyl-L-proline.
-
Umirolimus-d5
0 ImagesCat. No.: HY-122402SPurity: 99.96%Umirolimus-d5 is the deuterium labeled Umirolimus (HY-122402). Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications.
-
Beauvericin-13C45
0 ImagesCat. No.: HY-N6739SPurity: 98%Beauvericin-13C45 is 13C labeled Beauvericin (HY-N6739). Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages.
-
Bisphenol P-d16
0 ImagesCat. No.: HY-W654081CAS No.: 2469196-09-4Bisphenol P-d16 is deuterium labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene.
