Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11100)
Related Products (11100)
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L-Xylose-5-13C
0 ImagesSynonyms: L-(-)-Xylose-5-13C
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Sodium methanesulfinate-d3
0 ImagesSodium methanesulfinate-d3 is the deuterium labeled Sodium methanesulfinate.
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Mifepristone-d6
0 ImagesSynonyms: RU486-d6; RU 38486-d6Mifepristone-d6 is deuterated labeled Mifepristone (HY-13683). Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
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Clemastine-d5 fumarate
0 ImagesCat. No.: HY-B0298ASPurity: 99.79%Synonyms: HS-592-d5 fumarate; Meclastine-d5 fumarateClemastine (HS-592; Meclastine)-d5 fumarate is the deuterium labeled Clemastine fumarate. Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine fumarate also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine fumarate exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation .
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Pristanic acid-d3
0 ImagesCat. No.: HY-113024SCAS No.: 1383920-14-6Pristanic acid-d3 is deuterium labeled Pristanic acid. Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome.
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Cyhalothrin-d5
0 ImagesCyhalothrin-d5 is the deuterium labeled Cyhalothrin.
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Carfilzomib-d8
0 ImagesCarfilzomib-d8 is deuterium labeled Carfilzomib. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.
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Progesterone-13C3
0 ImagesSynonyms: Pregn-4-ene-3,20-dione-13C3Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
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N-Lactylleucine-13C6,15N
0 ImagesCat. No.: HY-164805SN-Lactylleucine-13C6,15N is the 15N- and 13C-labeled N-Lactylleucine (HY-164805). N-Lactylleucine is an endogenous N-lactoyl-amino acid formed from L-lactic acid and L-leucine. N-Lactylleucine has been detected in intermediate maple syrup urine disease.
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L-Cysteine-13C3,15N,d3
0 ImagesSynonyms: Cysteine-13C3,15N,d3L-Cysteine-13C3,15N,d3 is the deuterium, 13C-, and 15-labeled L-Isoleucine (HY-Y0337). L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.
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Hexazinone-d6
0 ImagesHexazinone-d6 is the deuterium labeled Hexazinone. Hexazinone is a triazinone herbicide with high mobility and persistence in soil. Hexazinone is mainly degraded by soil microorganisms, and its degradation and mineralization processes are significantly affected by soil texture (faster in clay loam) and application method (mixed application can improve its bioavailability and mineralization rate). Hexazinone exhibits mild to moderate acute oral toxicity and has significant eye irritation.
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L-Glutamine-15N2,d5
0 ImagesCat. No.: HY-N0390S7Synonyms: L-Glutamic acid 5-amide-15N2,d5L-Glutamine-15N2,d5 is the deuterium and 15N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na+-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity.
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Imazamox-13C,d3
0 ImagesCat. No.: HY-100427SPurity: 99.63%Synonyms: CL29926-13C,d3; (±)-Imazamox-13C,d3Imazamox-13C,d3 is the 13C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
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(4-NH2)-Exatecan-d5
0 ImagesCat. No.: HY-145397SPurity: 98.62%Synonyms: AZ14170132-d5(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan. (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs).
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Levocarnitine propionate-d9 hydrochloride
0 ImagesCat. No.: HY-B0932S2Purity: 99%Synonyms: L-Propionylcarnitine-d9 chlorideLevocarnitine propionate-d9 hydrochloride (L-Propionylcarnitine-d9 chloride) is deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is a ligand of carnitine acetyltransferase (CAT) with high enzyme affinity. Levocarnitine propionate hydrochloride possesses antioxidant activity. Levocarnitine propionate hydrochloride increases intracellular L-carnitine reserves. Levocarnitine propionate hydrochloride exerts a protective effect against myocardial ischemia-reperfusion injury. Levocarnitine propionate hydrochloride can be used in research related to myocardial ischemia-reperfusion injury and chronic ischemic heart disease.
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Sulindac-d3
0 ImagesCat. No.: HY-B0008SPurity: 99.38%Synonyms: MK-231-d3Sulindac-d3 is deuterium labeled Sulindac. Sulindac (MK-231) is a non-steroidal antiinflammatory agent, acts as a COX-2 inhibitor, and inhibits overexpression of COX-2.
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D-α-Hydroxyglutaric acid-13C5 (disodium)
0 ImagesCat. No.: HY-W779800CAS No.: 1648909-80-1D-α-Hydroxyglutaric acid-13C5 disodium is the 13C-labeled D-α-Hydroxyglutaric acid (HY-113038). D-α-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.
