2. Signaling Pathways
  3. Immunology/Inflammation
  4. LAG-3
  5. LAG-3 Ligand

LAG-3 Ligand

LAG-3 Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-P990243
    Anti-Mouse FGL-1 Antibody (177R4)
    		Ligand
    Anti-Mouse FGL-1 Antibody (177R4) is an anti-mouse FGL-1 IgG2a monoclonal antibody. Anti-Mouse FGL-1 Antibody (177R4) can increase CD8+ T cell infiltration. Anti-Mouse FGL-1 Antibody (177R4) enhances the anti-tumor immune effect by blocking FGL1. Anti-Mouse FGL-1 Antibody (177R4) can be used for research on cancer such as lung cancer and breast cancer.
  • HY-180900
    Z3071585108
    		Ligand
    Z3071585108 is a small molecule binder of the LAG-3 D1 domain with Kd values measured for the MST-TRIC channel and spectral shift detection of 59.2 and 56.1 μM respectively. Z3071585108 partially inhibits the binding of LAG-3 to MHCII, with an EC₅₀ of 42.9 μM. Z3071585108 can be used for the study of small molecule immunotherapies targeting LAG-3.