2. Signaling Pathways
  3. Immunology/Inflammation
  4. Transmembrane Glycoprotein
  5. Transmembrane Glycoprotein Agonist

Transmembrane Glycoprotein Agonist

Transmembrane Glycoprotein Agonists (7):

Cat. No. Product Name Effect Purity
  • HY-P0168
    Cibinetide
    		Agonist 99.86%
    Cibinetide (ARA290) is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide can be used in the research of neurological disorders.
  • HY-P1822
    BDC2.5 mimotope 1040-31
    		Agonist 99.75%
    BDC2.5 mimotope 1040-31, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells.
  • HY-P3844
    Biotinyl-neuropeptide W-23 (human)
    		Agonist 98.37%
    Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8).
  • HY-182724
    PSB-18422
    		Agonist
    PSB-18422 is a GPR17 agonist, with an EC50 of 0.0279 μM for humans, 0.47 μM for rats, 0.753 μM for mice, and a human Ki of 1.46 μM. PSB-18422 triggers intracellular calcium mobilization via cross-species activation of GPR17. PSB-18422 can be used in the research of allergic bronchial inflammation.
  • HY-P0168A
    Cibinetide acetate
    		Agonist
    Cibinetide (ARA290) acetate is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide acetate can be used in the research of neurological disorders.
  • HY-108864
    Epoetin alfa
    		Agonist
    Epoetin alfa (Epogen) is a recombinant human erythropoietin whose amino acid sequence and biological activity are identical to those of endogenous erythropoietin (EPO). Epoetin alfa is a direct agonist of the EPO receptor (EPOR) on the surface of erythroid progenitor cells, and promotes the production and maturation of red blood cells. Epoetin alfa can be used for research on myelodysplastic syndrome-related anemia and hematological malignancies.
  • HY-P991918
    KHK2840
    		Agonist
    KHK2840 is a potent CD40 agonist with a Kd value of 0.485 nM for hCD40. KHK2840 delivers agonistic signals in tumor-bearing hCD40 transgenic mice and human peripheral blood B cells. KHK2840 upregulates CD80, CD86, CD95 and IL-12p70 expression. KHK2840 enhances antitumor efficacy of anti-PD-1 antibody and Paclitaxel (HY-B0015). KHK2840 can be used for the research of cancer, such as colon cancer and melanoma.