Y-9738

Cat. No.: HY-100258: FAQs
Data Sheet Handling Instructions

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Y-9738 is a hypolipidemic agent.

For research use only. We do not sell to patients.

Y-9738 Chemical Structure

CAS No. : 59399-41-6

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Customer Review

Description	Y-9738 is a hypolipidemic agent.
In Vivo	Y-9738 is a hypolipidemic agent. At 100 mg/kg Y-9738 lowers the cholesterol level by 36% and clearly diminishes the intensity of the β-lipoprotein band with a tendency for the α-lipoprotein band to be intensified. Y-9738 causes a dose-dependent decrease in serum cholesterol, triglyceride and heparin-precipitable β-lipoprotein cholesterol. Furthermore, Y-9738 reduces the intensity of the β-lipoprotein band shown by electrophoresis, and increases that of the α-lipoprotein band^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	309.74
Formula	C₁₅H₁₆ClNO₄
CAS No.	59399-41-6
SMILES	O=C(OCC)CC1=C(OCC)OC(C2=CC=C(Cl)C=C2)=N1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Kobayakawa T, et al. Experimental hyper-beta-lipoproteinemia and its amelioration by a novel hypolipidemic agent. Atherosclerosis. 1978 Jul;30(3):219-25. [Content Brief]

Animal Administration
^[1]

Male Sprague-Dawley rats are used in this work. Rats (140 to 180 g) are fed a high cholesterol diet for 10 days. This diet contains 1% cholesterol, 0.2% sodium cholate and 5% olive oil. Y-9738 is orally administered to the animals once a day throughout the experimental period. All animals are starved overnight (about 20 h) after the last treatment and sacrificed by carotid incision. Blood and liver are collected for lipid analysis^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. Kobayakawa T, et al. Experimental hyper-beta-lipoproteinemia and its amelioration by a novel hypolipidemic agent. Atherosclerosis. 1978 Jul;30(3):219-25. [Content Brief]

Y-9738 Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Y-973859399-41-6Y9738Y 9738OthersInhibitorinhibitorinhibit

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Y-9738

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