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Y-9738 

Cat. No.: HY-100258
Handling Instructions

Y-9738 is a hypolipidemic agent.

For research use only. We do not sell to patients.

Y-9738 Chemical Structure

Y-9738 Chemical Structure

CAS No. : 59399-41-6

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Description

Y-9738 is a hypolipidemic agent.

In Vivo

Y-9738 is a hypolipidemic agent. At 100 mg/kg Y-9738 lowers the cholesterol level by 36% and clearly diminishes the intensity of the β-lipoprotein band with a tendency for the α-lipoprotein band to be intensified. Y-9738 causes a dose-dependent decrease in serum cholesterol, triglyceride and heparin-precipitable β-lipoprotein cholesterol. Furthermore, Y-9738 reduces the intensity of the β-lipoprotein band shown by electrophoresis, and increases that of the α-lipoprotein band[1].

References
Animal Administration
[1]

Male Sprague-Dawley rats are used in this work. Rats (140 to 180 g) are fed a high cholesterol diet for 10 days. This diet contains 1% cholesterol, 0.2% sodium cholate and 5% olive oil. Y-9738 is orally administered to the animals once a day throughout the experimental period. All animals are starved overnight (about 20 h) after the last treatment and sacrificed by carotid incision. Blood and liver are collected for lipid analysis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

309.74

Formula

C₁₅H₁₆ClNO₄

CAS No.

59399-41-6

SMILES

O=C(OCC)CC1=C(OCC)OC(C2=CC=C(Cl)C=C2)=N1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Y-9738
Cat. No.:
HY-100258
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Y-9738

Cat. No.: HY-100258