1. Metabolic Enzyme/Protease
  2. Isocitrate Dehydrogenase (IDH)
  3. (R,S)-Ivosidenib

(R,S)-Ivosidenib (Synonyms: (R,S)-AG-120)

Cat. No.: HY-18767A Purity: 98.61%
Handling Instructions

(R,S)-Ivosidenib ((R,S)-AG-120) is the less active enantiomer of Ivosidenib (AG-120).

For research use only. We do not sell to patients.

(R,S)-Ivosidenib Chemical Structure

(R,S)-Ivosidenib Chemical Structure

CAS No. : 2070009-31-1

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5 mg USD 96 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
50 mg USD 384 In-stock
Estimated Time of Arrival: December 31
100 mg USD 624 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

(R,S)-Ivosidenib ((R,S)-AG-120) is the less active enantiomer of Ivosidenib (AG-120)[1].

Molecular Weight

582.96

Formula

C₂₈H₂₂ClF₃N₆O₃

CAS No.

2070009-31-1

SMILES

FC1(F)CC(NC([[email protected]](N(C2=CC(F)=CN=C2)C([[email protected]@H](N3C4=NC=CC(C#N)=C4)CCC3=O)=O)C5=CC=CC=C5Cl)=O)C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.33 mg/mL (5.71 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7154 mL 8.5769 mL 17.1538 mL
5 mM 0.3431 mL 1.7154 mL 3.4308 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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(R,S)-Ivosidenib
Cat. No.:
HY-18767A
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