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Cat. No.: HY-169263

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AC10142A

AC10142A is a selective Adenylyl Cyclase Type 1 inhibitor with IC₅₀ of 0.26 μM. AC10142A can be used to study pain models.

For research use only. We do not sell to patients.

CAS No.: 2963581-29-3
Formula: C₁₈H₂₁N₅O
Molecular Weight:323.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

AC10142A Chemical Structure

CAS No.: 2963581-29-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AC10142A is a selective Adenylyl Cyclase Type 1 inhibitor with IC₅₀ of 0.26 μM. AC10142A can be used to study pain models^[1].

IC₅₀ & Target

IC50:0.26 μM（AC1）^[1]

Chemical Information

CAS No. 2963581-29-3
Molecular Weight 323.39
Formula C₁₈H₂₁N₅O
SMILES

C[C@@H](C1=CC=CC=C1)NC2=CC(C)=NN2C(NC(CC)=C3)=NC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shrinidhi A, et al. Pyrazolo-Pyrimidinones with Improved Solubility and Selective Inhibition of Adenylyl Cyclase Type 1 Activity for Treatment of Inflammatory Pain. J Med Chem. 2024 Oct 24;67(20):18290-18316. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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