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  3. Disease Research Fields Plants Alkaloids
  4. Inflammation/Immunology other families Isoquinoline Alkaloids
  5. Acetylcorynoline

Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties.

For research use only. We do not sell to patients.

Acetylcorynoline Chemical Structure

Acetylcorynoline Chemical Structure

CAS No. : 18797-80-3

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10 mg USD 130 In-stock
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Based on 1 publication(s) in Google Scholar

Acetylcorynoline Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1].

In Vitro

Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1].
Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Acetylcorynoline Related Antibodies
Molecular Weight

409.43

Formula

C23H23NO6
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CN1[C@]2([H])C(C(C[C@H](OC(C)=O)[C@]2(C)C3=C(C4=C(OCO4)C=C3)C1)=C5)=CC6=C5OCO6
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (61.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4424 mL 12.2121 mL 24.4242 mL
5 mM 0.4885 mL 2.4424 mL 4.8848 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.70%

COA (256 KB) HNMR (272 KB) LCMS (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4424 mL 12.2121 mL 24.4242 mL 61.0605 mL
5 mM 0.4885 mL 2.4424 mL 4.8848 mL 12.2121 mL
10 mM 0.2442 mL 1.2212 mL 2.4424 mL 6.1060 mL
15 mM 0.1628 mL 0.8141 mL 1.6283 mL 4.0707 mL
20 mM 0.1221 mL 0.6106 mL 1.2212 mL 3.0530 mL
25 mM 0.0977 mL 0.4885 mL 0.9770 mL 2.4424 mL
30 mM 0.0814 mL 0.4071 mL 0.8141 mL 2.0353 mL
40 mM 0.0611 mL 0.3053 mL 0.6106 mL 1.5265 mL
50 mM 0.0488 mL 0.2442 mL 0.4885 mL 1.2212 mL
60 mM 0.0407 mL 0.2035 mL 0.4071 mL 1.0177 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetylcorynoline18797-80-3OthersInhibitorinhibitorinhibit

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