2. PROTAC
  3. PROTAC Linkers
  4. Acid-PEG3-C2-Boc

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR.

For research use only. We do not sell to patients.

Acid-PEG3-C2-Boc Chemical Structure

Acid-PEG3-C2-Boc Chemical Structure

CAS No. : 1807539-06-5

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Based on 1 publication(s) in Google Scholar

Acid-PEG3-C2-Boc Related Antibodies

Top Publications Citing Use of Products

View All PROTAC Linkers Isoform Specific Products:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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  • Purity & Documentation

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Description

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Acid-PEG3-C2-Boc Related Antibodies
Molecular Weight

306.35

Formula

C14H26O7
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥97.0%

COA (241 KB) HNMR (115 KB) LCMS (234 KB)

Handling Instructions (2659 KB)
References
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Acid-PEG3-C2-Boc Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acid-PEG3-C2-Boc1807539-06-5PROTAC LinkersPROTAClinkermTOREGFRInhibitorinhibitorinhibit

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