1. PROTAC
  2. PROTAC Linker
  3. Acid-PEG3-C2-Boc

Acid-PEG3-C2-Boc 

Cat. No.: HY-130549
Handling Instructions

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR.

For research use only. We do not sell to patients.

Acid-PEG3-C2-Boc Chemical Structure

Acid-PEG3-C2-Boc Chemical Structure

CAS No. : 1807539-06-5

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Description

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

306.35

Formula

C₁₄H₂₆O₇

CAS No.

1807539-06-5

SMILES

CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Acid-PEG3-C2-BocPROTAC LinkerPROTAClinkermTOREGFRInhibitorinhibitorinhibit

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