Acolongifloroside K
Acolongifloroside K is a cardenolide toxin identified from the seeds of Strophanthus gratus. It exhibits acute cardiotoxicity, with acute toxicity comparable to that of Ouabain (HY-B1457). Acolongifloroside K is an active component in Maasai arrow poison prepared from Acokanthera schimperi. Acolongifloroside K can be used in studies related to cardiotoxicity and cardenolides.
For research use only. We do not sell to patients.
- CAS No.: 6251-64-5
- Formula: C29H44O12
- Molecular Weight:584.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Acolongifloroside K is the major active cardiac glycoside in Maasai arrow poison derived from Acokanthera schimperi (accounting for 5.3% by weight, which is 50% of total cardiac glycosides). It also exists in the seeds of Strophanthus gratus, accounting for approximately 0.4% of seed weight[1][2].
Acolongifloroside K accounts for approximately 0.40% of the seed weight of Strophanthus gratus. It can be isolated as filamentous acicular crystals with a melting point of 179-181°C, and is confirmed to be consistent with the standard reference substance via chromatographic, spectroscopic and hydrolytic analyses[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6251-64-5
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Molecular Weight 584.65
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Formula C29H44O12
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SMILES
OC[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@H](C[C@H]2O)O[C@H]4[C@@H]([C@@H]([C@@H]([C@@H](O4)C)O)O)O)O)([H])[C@@]5([C@](C[C@H]3O)([C@@H](C(CO6)=CC6=O)CC5)C)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cassels BK, et al. Analysis of a Maasai arrow poison. Journal of ethnopharmacology. 1985;14(2-3):273-81. [Content Brief]
[2]. Geiger UP, et al. Die Cardenolide der Samen von Strophanthus gratus (Wall. et Hook.) Franch. 2. Mitteilung [The cardenolides of the seeds from Strophanthus gratus(Wall. et Hook.) Franch. 2. Communication]. Helv Chim Acta. 1967 Jan 31;50(1):179-93. German. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Acolongifloroside K Related Classifications
HY-N20730 Related Classifications
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