Afatinib impurity 6
Based on 1 Customer Validation
Afatinib impurity 6 is an impurity of Afatinib (HY-10261).
For research use only. We do not sell to patients.
- Purity: 96.0%
- CAS No.: 1269662-90-9
- Formula: C16H14ClFN4O
- Molecular Weight:332.77
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 1269662-90-9
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Appearance Solid
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Molecular Weight 332.77
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Formula C16H14ClFN4O
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Color Off-white to yellow
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SMILES
NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (75.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0051 mL | 15.0254 mL | 30.0508 mL | 75.1270 mL |
| 5 mM | 0.6010 mL | 3.0051 mL | 6.0102 mL | 15.0254 mL | |
| 10 mM | 0.3005 mL | 1.5025 mL | 3.0051 mL | 7.5127 mL | |
| 15 mM | 0.2003 mL | 1.0017 mL | 2.0034 mL | 5.0085 mL | |
| 20 mM | 0.1503 mL | 0.7513 mL | 1.5025 mL | 3.7563 mL | |
| 25 mM | 0.1202 mL | 0.6010 mL | 1.2020 mL | 3.0051 mL | |
| 30 mM | 0.1002 mL | 0.5008 mL | 1.0017 mL | 2.5042 mL | |
| 40 mM | 0.0751 mL | 0.3756 mL | 0.7513 mL | 1.8782 mL | |
| 50 mM | 0.0601 mL | 0.3005 mL | 0.6010 mL | 1.5025 mL | |
| 60 mM | 0.0501 mL | 0.2504 mL | 0.5008 mL | 1.2521 mL |