AG-1859
AG-1859 is a viral protease inhibitor. AG-1859 can be used in the research of viral infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 478410-84-3
- 分子式: C27H33N3O5S
- 分子量:511.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
0.123 μM
Compound: 7k, KNI-1317
|
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
|
[PMID: 19954246] |
| MT4 | EC50 |
0.141 μM
Compound: 7k, KNI-1317
|
Antiviral activity against HIV1 pNL4-3 infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against HIV1 pNL4-3 infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
|
[PMID: 19954246] |
| MT4 | EC50 |
0.173 μM
Compound: 7k, KNI-1317
|
Antiviral activity against indinavir-resistant HIV1 harboring L10R/M46I/L63P/V82T/I84V mutant protease infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
Antiviral activity against indinavir-resistant HIV1 harboring L10R/M46I/L63P/V82T/I84V mutant protease infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay
|
[PMID: 19954246] |
化学情報
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CAS 番号 478410-84-3
-
分子量 511.63
-
分子式 C27H33N3O5S
-
SMILES
C=CCNC([C@H]1N(CSC1(C)C)C([C@@H](O)[C@@H](NC(C2=C(C(O)=CC=C2)C)=O)CC3=CC=CC=C3)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)