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Cat. No.: HY-19640

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AG-85

AG-85 is a major secretion protein of Mycobacterium tuberculosis, and can be identified in ancient bone.

For research use only. We do not sell to patients.

CAS No.: 152503-91-8
Formula: C₂₇H₂₂N₄O₃S
Molecular Weight:482.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

AG-85 Chemical Structure

CAS No.: 152503-91-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

AG-85 is a major secretion protein of Mycobacterium tuberculosis, and can be identified in ancient bone^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	1.3 μM Compound: 7	Inhibition of cellular growth against human (CCRF-CEM) leukemias (ATCC) deficient in thymidine kinase. Inhibition of cellular growth against human (CCRF-CEM) leukemias (ATCC) deficient in thymidine kinase.	[PMID: 2066965]
GC3/MTK-	IC₅₀	1.5 μM Compound: 7	Inhibition of cellular growth against human adenocarcinoma (GC3/M TK-) deficient in thymidine kinase. Inhibition of cellular growth against human adenocarcinoma (GC3/M TK-) deficient in thymidine kinase.	[PMID: 2066965]
L1210	IC₅₀	0.3 μM Compound: 7	Inhibition of cellular growth against mouse (L1210) deficient in thymidine kinase. Inhibition of cellular growth against mouse (L1210) deficient in thymidine kinase.	[PMID: 2066965]

Chemical Information

CAS No. 152503-91-8
Molecular Weight 482.55
Formula C₂₇H₂₂N₄O₃S
SMILES

O=C1N=C(NC2=C1C=C(CN(C3=CC=C(S(=O)(N4C=CC5=C4C=CC=C5)=O)C=C3)CC#C)C=C2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Schmidt-Schultz TH, et al. AG 85, a major secretion protein of Mycobacterium tuberculosis, can be identified in ancient bone. Tuberculosis (Edinb). 2015;95 Suppl 1:S87-S92. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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