Aganepag isopropyl
Based on 1 Customer Validation
Aganepag isopropyl (AGN-210961) is an EP2 agonist.
For research use only. We do not sell to patients.
- Purity: 98.23%
- CAS No.: 910562-20-8
- Formula: C27H37NO4S
- Molecular Weight:471.65
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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EP |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 910562-20-8
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Appearance Oil
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Molecular Weight 471.65
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Formula C27H37NO4S
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Color Colorless to light yellow
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SMILES
O=C(C1=CC=C(CCC[C@@H](CC2)N(C3=CC=C([C@@H](O)CCCCC)C=C3)C2=O)S1)OC(C)C
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Synonyms
AGN-210961
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (424.04 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Impagnatiello F, et al. Prostaglandin analogues and nitric oxide contribution in the treatment of ocular hypertension and glaucoma. Br J Pharmacol. 2019;176(8):1079-1089. [Content Brief]
[2]. Matsou A, et al. Investigational drugs targeting prostaglandin receptors for the treatment of glaucoma. Expert Opin Investig Drugs. 2018;27(10):777-785. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1202 mL | 10.6011 mL | 21.2022 mL | 53.0054 mL |
| 5 mM | 0.4240 mL | 2.1202 mL | 4.2404 mL | 10.6011 mL | |
| 10 mM | 0.2120 mL | 1.0601 mL | 2.1202 mL | 5.3005 mL | |
| 15 mM | 0.1413 mL | 0.7067 mL | 1.4135 mL | 3.5337 mL | |
| 20 mM | 0.1060 mL | 0.5301 mL | 1.0601 mL | 2.6503 mL | |
| 25 mM | 0.0848 mL | 0.4240 mL | 0.8481 mL | 2.1202 mL | |
| 30 mM | 0.0707 mL | 0.3534 mL | 0.7067 mL | 1.7668 mL | |
| 40 mM | 0.0530 mL | 0.2650 mL | 0.5301 mL | 1.3251 mL | |
| 50 mM | 0.0424 mL | 0.2120 mL | 0.4240 mL | 1.0601 mL | |
| 60 mM | 0.0353 mL | 0.1767 mL | 0.3534 mL | 0.8834 mL | |
| 80 mM | 0.0265 mL | 0.1325 mL | 0.2650 mL | 0.6626 mL | |
| 100 mM | 0.0212 mL | 0.1060 mL | 0.2120 mL | 0.5301 mL |
Aganepag isopropyl Related Classifications
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