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  3. AIE-Cbz-LD-C7

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER).

For research use only. We do not sell to patients.

AIE-Cbz-LD-C7 Chemical Structure

AIE-Cbz-LD-C7 Chemical Structure

CAS No. : 2810130-33-5

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Description

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER)[1].

In Vitro

AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility[1].
AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability[1].
AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity[1].
AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: HepG2 cells
Concentration: 0, 2, 5, 10, 20, and 30 μM
Incubation Time: 24 h
Result: Displayed favorable viability with a value above 90%.
Molecular Weight

510.67

Formula

C35H34N4

CAS No.
SMILES

CCCCCCCN1C2=C(C3=C1C=CC(/C=C/C4=C/C(C5=CC=CC=C5N4CC)=C(C#N)/C#N)=C3)C=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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AIE-Cbz-LD-C7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AIE-Cbz-LD-C7
Cat. No.:
HY-151468
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