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Cat. No.: HY-151468

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AIE-Cbz-LD-C7

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER).

For research use only. We do not sell to patients.

CAS No.: 2810130-33-5
Formula: C₃₅H₃₄N₄
Molecular Weight:510.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

AIE-Cbz-LD-C7 Chemical Structure

CAS No.: 2810130-33-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility^[1].
AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability^[1].
AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity^[1].
AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HepG2 cells
Concentration:

0, 2, 5, 10, 20, and 30 μM
Incubation Time:

24 h
Result:

Displayed favorable viability with a value above 90%.

Chemical Information

CAS No. 2810130-33-5
Molecular Weight 510.67
Formula C₃₅H₃₄N₄
SMILES

CCCCCCCN1C2=C(C3=C1C=CC(/C=C/C4=C/C(C5=CC=CC=C5N4CC)=C(C#N)/C#N)=C3)C=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rui Chen, et al. Rational Design of Novel Lipophilic Aggregation-Induced Emission Probes for Revealing the Dynamics of Lipid Droplets during Lipophagy and Ferroptosis. Anal Chem. 2022 Sep 19. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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