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Cat. No.: HY-139158

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Ainuovirine

Name: Ainuovirine
Brand: MedChemExpress
SKU: HY-139158
Price: 294.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Ainuovirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Ainuovirine inhibits HIV replication by non-competitively binding to HIV reverse transcriptase and blocking the reverse transcription process of viral RNA. Ainuovirine can be used for human immunodeficiency virus (HIV) type 1 infection.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1097628-00-6
Formule: C₁₈H₁₉N₃O₃
Masse moléculaire:325.36

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ainuovirine Chemical Structure

CAS No.: 1097628-00-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	EC₅₀	6.1 nM Compound: 10b	Antiviral activity against wild type HIV1 infected in human MT2 cells Antiviral activity against wild type HIV1 infected in human MT2 cells	[PMID: 20138513]
MT2	EC₅₀	6.4 nM Compound: 10b	Antiviral activity against NNRTI-resistant HIV1 harboring reverse transcriptase K103N mutant infected in human MT2 cells Antiviral activity against NNRTI-resistant HIV1 harboring reverse transcriptase K103N mutant infected in human MT2 cells	[PMID: 20138513]
MT2	EC₅₀	9.6 nM Compound: 10b	Antiviral activity against HIV1 harboring reverse transcriptase Y181C mutant infected in human MT2 cells Antiviral activity against HIV1 harboring reverse transcriptase Y181C mutant infected in human MT2 cells	[PMID: 20138513]

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Chemical Information

CAS No. 1097628-00-6
Masse moléculaire 325.36
Formule C₁₈H₁₉N₃O₃
SMILES

N#CC1=CC(C)=CC(C(C2=C(C(C)C)C(NC(N2CC)=O)=O)=O)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cha Y J, et al. Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse-transcriptase inhibitor KM-023 in healthy subjects[J]. Drug Design, Development and Therapy, 2014: 1613-1619. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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