Aminooxy-PEG3-acid
Based on 1 Customer Validation
Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 1807540-79-9
- Formula: C9H19NO6
- Molecular Weight:237.25
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1807540-79-9
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Appearance Oil
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Molecular Weight 237.25
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Formula C9H19NO6
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Color Colorless to light yellow
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SMILES
O=C(O)CCOCCOCCOCCON
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 250 mg/mL (1053.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2150 mL | 21.0748 mL | 42.1496 mL | 105.3741 mL |
| 5 mM | 0.8430 mL | 4.2150 mL | 8.4299 mL | 21.0748 mL | |
| 10 mM | 0.4215 mL | 2.1075 mL | 4.2150 mL | 10.5374 mL | |
| 15 mM | 0.2810 mL | 1.4050 mL | 2.8100 mL | 7.0249 mL | |
| 20 mM | 0.2107 mL | 1.0537 mL | 2.1075 mL | 5.2687 mL | |
| 25 mM | 0.1686 mL | 0.8430 mL | 1.6860 mL | 4.2150 mL | |
| 30 mM | 0.1405 mL | 0.7025 mL | 1.4050 mL | 3.5125 mL | |
| 40 mM | 0.1054 mL | 0.5269 mL | 1.0537 mL | 2.6344 mL | |
| 50 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1075 mL | |
| 60 mM | 0.0702 mL | 0.3512 mL | 0.7025 mL | 1.7562 mL | |
| 80 mM | 0.0527 mL | 0.2634 mL | 0.5269 mL | 1.3172 mL | |
| 100 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL |