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  3. Anhydrotetracycline hydrochloride

Anhydrotetracycline hydrochloride 

Cat. No.: HY-118660
Handling Instructions

Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene expression systems in eukaryotic cells.

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Anhydrotetracycline hydrochloride Chemical Structure

Anhydrotetracycline hydrochloride Chemical Structure

CAS No. : 13803-65-1

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Description

Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene expression systems in eukaryotic cells[1].

In Vitro

Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline[1].
Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline[1].

Molecular Weight

462.88

Formula

C₂₂H₂₃ClN₂O₇

CAS No.

13803-65-1

SMILES

O=C(C(C1=O)=C(O)[[email protected]@H](N(C)C)[[email protected]]2([H])CC3=C(C([[email protected]@]21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

AnhydrotetracyclineAntibioticBacterialtetracyclinebiosyntheticdestructaseenzymeseukaryoticchlortetracyclinedemeclocyclineTet50Inhibitorinhibitorinhibit

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Anhydrotetracycline hydrochloride
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