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Cat. No.: HY-115971

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Anti-Trypanosoma cruzi agent-1

Anti-Trypanosoma cruzi agent-1 (Compd E5) posseses anti-T. gondii activity.

For research use only. We do not sell to patients.

CAS No.: 2854299-38-8
Formula: C₂₃H₂₉N₃O₅
Molecular Weight:427.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Anti-Trypanosoma cruzi agent-1 Chemical Structure

CAS No.: 2854299-38-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Anti-Trypanosoma cruzi agent-1 (Compd E5) posseses anti-T. gondii activity^[1].

IC₅₀ & Target

Trypanosoma

Toxoplasma

All Parasite Isoforms :

In Vitro

Anti-Trypanosoma cruzi agent-1 (Compd E5) demonstrates the strongest activity, and the IC50 against HFF-1 (Human Foreskin Fibroblasts-1) cells following infection with T. gondii is 80.9 μM (MPA-211.5 μM) and its selectivity value is 2.2 (MPA-1.2)^[1].
Anti-Trypanosoma cruzi agent-1 (Compd E5) is able to alleviate hepatomegaly and splenomegaly caused by acute Toxoplasma infection^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2854299-38-8
Molecular Weight 427.49
Formula C₂₃H₂₉N₃O₅
SMILES

COC1=C(C2=C(C(O)=C1C/C=C(CCC(NCCCN3C=CN=C3)=O)\C)C(OC2)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fan-Fan Shang, et al. Synthesis and Evaluation of Mycophenolic Acid Derivatives as Potential Anti-Toxoplasma Gondii. Research Square.2021 Oct.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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