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Cat. No.: HY-174407

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Antibacterial agent 281

Antibacterial agent 281 (Compound 95,186) can bacteriostatically inhibit the growth of GAS. Antibacterial agent 281 binds to the ligand binding pocket of SPs0871 and competes with the ligand. Antibacterial agent 281 shows concentration-dependent growth inhibition against S. pyogenes.

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CAS No.: 585553-10-2
Formule: C₂₃H₂₄N₆O
Masse moléculaire:400.48

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Antibacterial agent 281 Chemical Structure

CAS No.: 585553-10-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 585553-10-2
Masse moléculaire 400.48
Formule C₂₃H₂₄N₆O
SMILES

O=C(NC1=CC=CC(C2=NN=C3N2N=C(C)C4=CC=CC=C43)=C1)CN5CCCCC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Signal Pathway Related

Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yamawaki T, et al., Development of a small compound that regulates the function of a maltodextrin-binding protein of Streptococcus pyogenes by multifaceted screenings. Sci Rep. 2025 Jun 2;15(1):19341. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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