Carboxypeptidase A1/A2/B Antibody (YA2486)

Cat. No.: HY-P82741: Data Sheet COA
SDS
User Guide for Antibodies
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Carboxypeptidase A1/A2/B Antibody (YA2486) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Carboxypeptidase A1/A2/B.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Carboxypeptidase A1/A2/B Antibody (YA2486) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation
References

Description

Carboxypeptidase A1/A2/B Antibody (YA2486) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Carboxypeptidase A1/A2/B.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 47 kDa;

Observed band size: 44 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P15085 / P15086 / P48052

Gene ID

1357 [NCBI] / 1360 [NCBI] / 1358 [NCBI]

Immunogen

A synthesized peptide derived from human Carboxypeptidase A1(P15085) AA360-419 aa360-419/419.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

IHC-P

Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using Carboxypeptidase A1A2B Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using Carboxypeptidase A1A2B Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

Function：P15085: Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:20385563, PubMed:8806703). Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity)
P48052: Carboxypeptidase that catalyzes the release of a C-terminal amino acid, with a preference for large aromatic C-terminal residues

Subcellular Localization：P15085: Secreted
P15086: Secreted; Zymogen granule lumen
P48052: Secreted

Expression：
Tissue_specificity: P15086: Pancreas

Isoforms & Post-Translational Modification：Human (P15085): 419 amino acids, molecular weight 47,140 Da.
Human (P15086): 417 amino acids, molecular weight 47,368 Da.
Human (P48052): 419 amino acids, molecular weight 47,030 Da.

Subunit：P15085: Monomer. May form a complex with proelastase 2

RRID

AB_3104839

Database

Entrez Gene: 1357 Human ; 1360 Human ; 1358 Human

SwissProt: P15085 Human ; P15086 Human ; P48052

Research Field

Synonyms

Carboxypeptidase A1+A2+B

Documentation

Select Batch:

Data Sheet (231 KB) SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/ht-29-cell.html [Content Brief]

Carboxypeptidase A1/A2/B Antibody (YA2486) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Carboxypeptidase A1/A2/B Antibody (YA2486)

Carboxypeptidase A1/A2/B Antibody (YA2486) Featured Recommendations:

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Carboxypeptidase A1/A2/B Antibody (YA2486) Related Classifications

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