CD75 Antibody
(Synonyms: SIAT1, ST6GAL1, B-cell antigen CD75, ST6Gal I, Sialyltransferase 1, ST6GalI)CD75 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CD75.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Antibody Dilution Buffer (for Immunohistochemistry, IHC)
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Antibody Labeling Kit-VF 488
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Antibody Dilution Buffer (for Immunostaining)
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DAB Peroxidase Substrate Kit (Purple-Blue Color)
HY-K1107
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TBS-T Powder (1 L of 1×)
HY-K1025
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PBS Buffer (1×)
HY-K3005
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PBS-T Powder (1 L of 1×)
HY-K1022
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TBS Powder (1 L of 1×)
HY-K1026
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AntiFade Mounting Medium (with DAPI)
HY-K1047
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AntiFade Reagent (with DAPI)
HY-K1048
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0.25% Trypsin-EDTA (1×), no phenol red
HY-K3009
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GelHP Protein Gel (Tris-Gly, 10%, 10 well)
HY-K1111
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
CD75 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CD75.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
Synthetic peptide corresponding to the center region of human CD75.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD75 transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. In B lymphocytes, generates neuraminidase-sensitive lymphocyte cell-surface differentiation antigens, such as CDw75, HB-6 and CD76. Sialylates complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs confering anti-inflammatory effector functions. Preferentially monosialylates the alpha(1->3) mannose antenna of Fc glycoforms with subsequent disialylation occurring at a much slower rate[1].
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Subcellular Localization
Golgi apparatus, Golgi stack membrane; Secreted
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Isoforms & Post-Translational Modification
CD75 has 2 isoforms, P15907-1: amino acid length is 406, molecular weight is 46605 Da (predicted); P15907-2: amino acid length is 175, molecular weight is 20764 Da (predicted).N-glycosylated
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Subunit
Monomer and homodimer
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SwissProt ID
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Synonyms
SIAT1, ST6GAL1, B-cell antigen CD75, ST6Gal I, Sialyltransferase 1, ST6GalI
Documentation
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