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  4. Muntingiaceae Monophenols
  5. Muntingia calabura L.
  6. Anticancer agent 182

Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity.

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Anticancer agent 182

Anticancer agent 182 Chemical Structure

CAS No. : 133342-90-2

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Anticancer agent 182 Related Antibodies

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Description

Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity[1].

Cellular Effect
Cell Line Type Value Description References
Col2 ED50
> 20 μg/mL
Compound: 1
Cytotoxicity against human Col2 cells
Cytotoxicity against human Col2 cells
[PMID: 2045815]
HT-1080 ED50
> 20 μg/mL
Compound: 1
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
[PMID: 2045815]
KB ED50
13.3 μg/mL
Compound: 1
Cytotoxicity against vincristine-resistant human KB cells
Cytotoxicity against vincristine-resistant human KB cells
[PMID: 2045815]
KB ED50
9.4 μg/mL
Compound: 1
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
[PMID: 2045815]
Lu1 ED50
> 20 μg/mL
Compound: 1
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
[PMID: 2045815]
P388 ED50
5.9 μg/mL
Compound: 1
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
[PMID: 2045815]
SK-MEL-2 ED50
14.6 μg/mL
Compound: 1
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
[PMID: 2045815]
Molecular Weight

316.35

Formula

C18H20O5
CAS No.
SMILES

OC1=CC([C@@H]2CCC3=CC=C(OC)C=C3O2)=CC(OC)=C1OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anticancer agent 182 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 182133342-90-2Anticancer agent182Anticancer agent-182OthersMuntingia colabura L.cytotoxicityAnticancerFlavonoidInhibitorinhibitorinhibit

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