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Cat. No.: HY-184838

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Anticancer agent 339 maleate

Anticancer agent 339 maleate is an anticancer agent derived from Tanshinone I (HY-N0134), with selective antiproliferative activity against cancer cells and drug-resistant cancer cells. Anticancer agent 339 maleate can be used in research related to various cancers including colon cancer.

For research use only. We do not sell to patients.

CAS No.: 2231762-25-5
Formula: C₂₄H₂₁NO₇
Molecular Weight:435.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Anticancer agent 339 maleate Chemical Structure

CAS No.: 2231762-25-5

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Chemical Information
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Biological Activity

Description

In Vitro

Anticancer agent 339 (Compound 8a) maleate (72 h) exhibits the strongest antiproliferative activity against human oral squamous carcinoma KB cells and Vincristine (HY-N0488A)-resistant KB/VCR multidrug-resistant tumor cells, with an IC₅₀ of 1.11 μM for KB cells and 0.51 μM for KB/VCR cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2231762-25-5
Molecular Weight 435.43
Formula C₂₄H₂₁NO₇
SMILES

OC(/C=C\C(O)=O)=O.O=C1C2=C(C=CC=C3C)C3=CC=C2C4=C(C(CN(C)C)=CO4)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ding C, et al. Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties. Journal of medicinal chemistry. 2018 Feb 08;61(3):760-776. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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