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Antiproliferative agent-20 is a potent and orally active anticancer agent. Antiproliferative agent-20 exhibits antiproliferative and anti-angiogenic activities.

For research use only. We do not sell to patients.

Antiproliferative agent-20 Chemical Structure

Antiproliferative agent-20 Chemical Structure

CAS No. : 1344715-94-1

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Description

Antiproliferative agent-20 is a potent and orally active anticancer agent. Antiproliferative agent-20 exhibits antiproliferative and anti-angiogenic activities[1].

In Vitro

Antiproliferative agent-20 (compound 5) (3.125 -50.0 μM; 24-96 h) inhibits the proliferation of Bel-7402 cells in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Antiproliferative agent-20 (10-40 μg/egg) inhibits the angiogenesis of the chick chorioallantoic membrane (CAM)[1].
Antiproliferative agent-20 (3.2 g/kg; p.o.) shows no deaths or signs of toxicity in mice during two weeks[1].
Antiproliferative agent-20 (24 h) does not be hydrolyzed in 37℃ artificial gastric juice and artificial intestinal liquid[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

418.40

Formula

C23H18N2O6

CAS No.
SMILES

O=C(C(C=C1C2=O)=CC(O)=C1C(C3=C2C=CC=C3O)=O)OCC4=NC(C)=C(C)N=C4C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Antiproliferative agent-20 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antiproliferative agent-20
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HY-142085
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