Antiproliferative agent-51
Antiproliferative agent-51 (Compound 18h) exhibits inhibitory efficacy against estrogen receptor α (ERα) mediated transcription, with an IC50 of 1.6 nM. Antiproliferative agent-51 inhibits the proliferation of cancer cell ZR-75, with an IC50 of 0.031 μM. Antiproliferative agent-51 exhibits antitumor efficacy in mouse models.
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- Formel: C43H50N4O9
- Molecular Weight:766.88
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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Molecular Weight 766.88
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Formel C43H50N4O9
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SMILES
O=C(C1=CC(OCCO)=C(C=C1)[N+]([O-])=O)NC2=CC=C(C=C2OCC(C)C)C(NC3=CC=C(C=C3OCC(C)C)C(N[C@@H]4CC[C@H](CC4)C5=CC=CC=C5)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)