Antitumor agent-114
Antitumor agent-114 is a potent stimulator of interferon genes (STING) agonist. Antitumor agent-114 activates immunity and reduces tumor volume in a mouse model of breast cancer. Antitumor agent-114 can be used for immunity and cancer diseases research.
For research use only. We do not sell to patients.
- CAS No.: 2757762-91-5
- Formula: C39H50F2N10O13P2
- Molecular Weight:966.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:4T1 tumor-bearing mice model[1]
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Dosage:2, 0.67, 0.22 mg/kg
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Administration:Intratumoral (i.t.)
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Result:Reached 80 and 70% tumor growth inhibition (TGI) in the groups treated with 2 and 0.67 mg/kg.
Induced tumor regression in 7 of 8 mice at a dose of 2 mg/kg.
Chemical Information
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CAS No. 2757762-91-5
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Molecular Weight 966.82
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Formula C39H50F2N10O13P2
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SMILES
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP4(OCOC(C5(C)CCCCC5)=O)=O)[C@@H](OP(OCOC(C6(C)CCCCC6)=O)(C=C[C@@H]7[C@@H](O4)[C@@H](F)[C@H](N8C(N=CN=C9N)=C9N=C8)O7)=O)[C@H]3F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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