Antiviral agent 54
Antiviral agent 54 (compound 33) is a broad-spectrum and orally active antiviral agent. Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA). Antiviral agent 54 decreases the ZIKV RNA and protein level.
For research use only. We do not sell to patients.
- Formula: C23H37N7
- Molecular Weight:411.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 0.39 µM (ZIKV); 2.28 µM (HCoV-OC43); 2.69 µM (influenza A)[1]
Antiviral agent 54 (compound 33) (5, 2.5, 1.25, 0.625 µM; 48 h) decreases the ZIKV NS5 protein and RNA level in a dose-dependent manner[1].
Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA) with EC50s of 0.39, 2.28, 2.69 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HUVEC cells
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Concentration:5, 2.5, 1.25, 0.625 µM
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Incubation Time:48 h
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Result:Decreased the ZIKV NS5 protein level in a dose-dependent manner.
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Cell Line:HUVEC cells
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Concentration:10 µM
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Incubation Time:48 h
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Result:Decreased the ZIKV RNA level in a dose-dependent manner.
Chemical Information
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Molecular Weight 411.59
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Formula C23H37N7
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SMILES
CN(C)CCN(C)CCN(C)C1=CC=NC(CN2CCN(C3=CC=NC=C3)CC2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiviral agent 54 Related Classifications
HY-161454 Related Classifications
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