AR ligand-30
AR ligand-30 is a target protein ligand for PROTAC Bavdegalutamide (HY-138641), which can be used in prostate cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2505498-73-5
- Formula: C18H16Cl2N4O2
- Molecular Weight:391.25
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2505498-73-5
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Appearance Solid
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Molecular Weight 391.25
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Formula C18H16Cl2N4O2
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Color White to off-white
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SMILES
O=C(C1=NN=C(Cl)C=C1)N[C@H]2CC[C@H](OC3=CC=C(C#N)C(Cl)=C3)CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (127.80 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5559 mL | 12.7796 mL | 25.5591 mL | 63.8978 mL |
| 5 mM | 0.5112 mL | 2.5559 mL | 5.1118 mL | 12.7796 mL | |
| 10 mM | 0.2556 mL | 1.2780 mL | 2.5559 mL | 6.3898 mL | |
| 15 mM | 0.1704 mL | 0.8520 mL | 1.7039 mL | 4.2599 mL | |
| 20 mM | 0.1278 mL | 0.6390 mL | 1.2780 mL | 3.1949 mL | |
| 25 mM | 0.1022 mL | 0.5112 mL | 1.0224 mL | 2.5559 mL | |
| 30 mM | 0.0852 mL | 0.4260 mL | 0.8520 mL | 2.1299 mL | |
| 40 mM | 0.0639 mL | 0.3195 mL | 0.6390 mL | 1.5974 mL | |
| 50 mM | 0.0511 mL | 0.2556 mL | 0.5112 mL | 1.2780 mL | |
| 60 mM | 0.0426 mL | 0.2130 mL | 0.4260 mL | 1.0650 mL | |
| 80 mM | 0.0319 mL | 0.1597 mL | 0.3195 mL | 0.7987 mL | |
| 100 mM | 0.0256 mL | 0.1278 mL | 0.2556 mL | 0.6390 mL |