2. Vitamin D Related/Nuclear Receptor PROTAC
  3. Androgen Receptor Ligands for Target Protein for PROTAC
  4. AR ligand-30

AR ligand-30 is a target protein ligand for PROTAC Bavdegalutamide (HY-138641), which can be used in prostate cancer research.

For research use only. We do not sell to patients.

AR ligand-30

AR ligand-30 Chemical Structure

CAS No. : 2505498-73-5

Size Price Stock Quantity
5 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
10 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
25 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
50 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
100 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
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Based on 1 publication(s) in Google Scholar

AR ligand-30 Related Antibodies

Top Publications Citing Use of Products

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  • Purity & Documentation

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Description

AR ligand-30 is a target protein ligand for PROTAC Bavdegalutamide (HY-138641), which can be used in prostate cancer research[1].

Molecular Weight

391.25

Formula

C18H16Cl2N4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NN=C(Cl)C=C1)N[C@H]2CC[C@H](OC3=CC=C(C#N)C(Cl)=C3)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (127.80 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5559 mL 12.7796 mL 25.5591 mL
5 mM 0.5112 mL 2.5559 mL 5.1118 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5559 mL 12.7796 mL 25.5591 mL 63.8978 mL
5 mM 0.5112 mL 2.5559 mL 5.1118 mL 12.7796 mL
10 mM 0.2556 mL 1.2780 mL 2.5559 mL 6.3898 mL
15 mM 0.1704 mL 0.8520 mL 1.7039 mL 4.2599 mL
20 mM 0.1278 mL 0.6390 mL 1.2780 mL 3.1949 mL
25 mM 0.1022 mL 0.5112 mL 1.0224 mL 2.5559 mL
30 mM 0.0852 mL 0.4260 mL 0.8520 mL 2.1299 mL
40 mM 0.0639 mL 0.3195 mL 0.6390 mL 1.5974 mL
50 mM 0.0511 mL 0.2556 mL 0.5112 mL 1.2780 mL
60 mM 0.0426 mL 0.2130 mL 0.4260 mL 1.0650 mL
80 mM 0.0319 mL 0.1597 mL 0.3195 mL 0.7987 mL
100 mM 0.0256 mL 0.1278 mL 0.2556 mL 0.6390 mL
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AR ligand-30 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AR ligand-302505498-73-5AR ligand30AR ligand 30Androgen ReceptorLigands for Target Protein for PROTACTarget Protein-binding MoietyPROTAC target protein ligandcancerInhibitorinhibitorinhibit

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