2. PROTAC
  3. LYTACs
  4. ASGPR ligand-2

ASGPR ligand-2 (Compound 366) is an asialoglycoprotein receptor (ASGPR) binder. ASGPR ligand-2 can be coupled with recognition elements of target proteins (such as antibodies or antigen-binding fragments), and through the endocytosis mediated by ASGPR, the target protein is delivered to the lysosomes of liver cells, promoting the degradation of the target protein. ASGPR ligand-2 can be used for the research of metabolic disease.

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ASGPR ligand-2

ASGPR ligand-2 Chemical Structure

CAS No. : 3062599-51-0

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ASGPR ligand-2 Related Antibodies

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Description

ASGPR ligand-2 (Compound 366) is an asialoglycoprotein receptor (ASGPR) binder. ASGPR ligand-2 can be coupled with recognition elements of target proteins (such as antibodies or antigen-binding fragments), and through the endocytosis mediated by ASGPR, the target protein is delivered to the lysosomes of liver cells, promoting the degradation of the target protein. ASGPR ligand-2 can be used for the research of metabolic disease[1].

Molecular Weight

682.72

Formula

C27H50N6O14
CAS No.
SMILES

[N-]=[N+]=NCCOCCOCCOCC(NCCOCCC(NCCOCCOCCO[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)NC(C)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ASGPR ligand-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ASGPR ligand-23062599-51-0ASGPR ligand2ASGPR ligand 2LYTACsLysosome-targeting chimerasInhibitorinhibitorinhibit

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