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Art. -Nr.: HY-128498

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Anticancer agent 182

Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity.

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CAS. Nr.: 133342-90-2
Formel: C₁₈H₂₀O₅
Molecular Weight:316.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Anticancer agent 182 Chemical Structure

CAS. Nr.: 133342-90-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BC1 cell line	ED₅₀	>20 μg/mL Compound: 1	Cytotoxicity against human BC1 cells Cytotoxicity against human BC1 cells	[PMID: 2045815]
Col2	ED₅₀	>20 μg/mL Compound: 1	Cytotoxicity against human Col2 cells Cytotoxicity against human Col2 cells	[PMID: 2045815]
HT-1080	ED₅₀	>20 μg/mL Compound: 1	Cytotoxicity against human HT1080 cells Cytotoxicity against human HT1080 cells	[PMID: 2045815]
KB	ED₅₀	13.3 μg/mL Compound: 1	Cytotoxicity against vincristine-resistant human KB cells Cytotoxicity against vincristine-resistant human KB cells	[PMID: 2045815]
KB	ED₅₀	9.4 μg/mL Compound: 1	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 2045815]
Lu1	ED₅₀	>20 μg/mL Compound: 1	Cytotoxicity against human Lu1 cells Cytotoxicity against human Lu1 cells	[PMID: 2045815]
P388	ED₅₀	5.9 μg/mL Compound: 1	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 2045815]
SK-MEL-2	ED₅₀	14.6 μg/mL Compound: 1	Cytotoxicity against human SK-MEL-2 cells Cytotoxicity against human SK-MEL-2 cells	[PMID: 2045815]

Chemical Information

CAS. Nr. 133342-90-2
Molecular Weight 316.35
Formel C₁₈H₂₀O₅
SMILES

OC1=CC([C@@H]2CCC3=CC=C(OC)C=C3O2)=CC(OC)=C1OC
Structure Classification
- Phenols
- Monophenols
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Kaneda, N et al. Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots. Journal of natural products vol. 54,1 (1991): 196-206. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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