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Art. -Nr.: HY-178233

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CAT335

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3032789-44-6
Formel: C₁₈H₁₂Cl₂N₂O₃
Molecular Weight:375.21

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CAT335 Chemical Structure

CAS. Nr.: 3032789-44-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure^[1].

Chemical Information

CAS. Nr. 3032789-44-6
Molecular Weight 375.21
Formel C₁₈H₁₂Cl₂N₂O₃
SMILES

O=C1C=CC(N1C2=CC=C(C(NCC3=CC=C(C=C3Cl)Cl)=O)C=C2)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Adam R. RENSLO, et al. Covalent, chemogenetic activators for k2p potassium channels and uses thereof. WO2024064923A2. WIPO (PCT). 2023-09-22.

[2]. Deal PE, et al. Development of covalent chemogenetic K2P channel activators. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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