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Art. -Nr.: HY-187606

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DB293

DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences.

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CAS. Nr.: 216308-19-9
Formel: C₁₉H₁₆N₆O
Molecular Weight:344.37

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

DB293 Chemical Structure

CAS. Nr.: 216308-19-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

DB293 (20 μM) forms a cooperative 2:1 dimer with the ATGA sequence and 1:1 monomer complexes with ATATAT and AAATTT sequences, with the highest affinity observed for the ATGA dimer^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 216308-19-9
Molecular Weight 344.37
Formel C₁₉H₁₆N₆O
SMILES

N=C(C1=CC=C(C2=CC=C(C3=NC4=CC=C(C(N)=N)C=C4N3)O2)C=C1)N
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Laughlin S, et al. A novel approach using electrospray ionization mass spectrometry to study competitive binding of small molecules with mixed DNA sequences. Analytical and bioanalytical chemistry. 2014 Oct;406(25):6441-5.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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