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Art. -Nr.: HY-N21759

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Dendroside D

Dendroside D is a sesquiterpenoid compound. Dendroside D binds to the RNA site of RNA-dependent RNA polymerase and the active site of SARS-CoV-2 main protease through hydrogen bonds, electrostatic interactions, and hydrophobic interactions, thereby blocking viral replication. Dendroside D stimulates the proliferation of mouse T and B lymphocytes, promotes T and B lymphocyte proliferation, and exhibits immunomodulatory activity. Dendroside D can be used for viral infection and immune-related research.

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CAS. Nr.: 503443-09-2
Formel: C₂₇H₄₄O₁₄
Molecular Weight:592.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Dendroside D Chemical Structure

CAS. Nr.: 503443-09-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- In Vitro
Chemical Information
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Biologische Aktivität

Beschreibung

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In Vitro

Adaptive ImmunityOthers

Adaptive Immunity

Dendroside D promotes the proliferation of T and B lymphocytes^[3].

Others

Dendroside D exhibits binding affinity to HAase with a docking score of -6.701 Kcal/mol in the molecular docking model^[1].
Dendroside D (15 mg; 7 days) is a glycoside that yields aglycone 1a and glucose upon enzymatic hydrolysis with β-cellulase^[2].
The sugar moiety of Dendroside D (0.04 M; 1 h) is D-glucose, as confirmed by GLC retention time matching authentic D-glucose^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 503443-09-2
Molecular Weight 592.64
Formel C₂₇H₄₄O₁₄
SMILES

C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@@]2(C)[C@@]3([C@]2(CC[C@](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(O)[C@@]5([C@]3([C@H](C)CC5)[H])[H])[H])[H]
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Mohamed EM, et al. Bioassay-Guided Isolation, Metabolic Profiling, and Docking Studies of Hyaluronidase Inhibitors from Ravenala madagascariensis. Molecules. 2020 Apr 8;25(7):1714.

[2]. Ye Q, et al. Immunomodulatory sesquiterpene glycosides from Dendrobium nobile. Phytochemistry. 2002 Dec;61(8):885-90.

[3]. Li J, et al. The Chemical Structure and Pharmacological Activity of Sesquiterpenoids in Dendrobium Sw. Molecules. 2024 Dec 11;29(24):5851.

[4]. Rafli M, et al. Potential of Dendrobium spp. Secondary Metabolites as Medicinal Source for SARS‑CoV‑2. In: Proceedings of the 7th International Conference on Biological Science (ICBS 2021); 2021 Oct 14‑15; Yogyakarta, Indonesia. Advances in Biological Sciences Research. Atlantis Press; 2022.

[5]. Kinasih A, et al In Silico Study of Secondary Metabolites in Dendrobium spp. as SARS‑CoV‑2 Antivirus on Main Protease (Mpro). Jurnal Riset Biologi dan Aplikasinya. 2022 Mar;4(1):19‑25.

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dendroside D

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