DHPCC-9
DHPCC-9 acts as an inhibitor of Pim kinase.
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- CAS. Nr.: 1192248-37-5
- Formel: C15H10N2O
- Molecular Weight:234.25
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
26 μM
Compound: 9
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Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
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[PMID: 19788246] |
| DU-145 | IC50 |
26 μM
Compound: A
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Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| DU-145 | IC50 |
26 μM
Compound: A
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Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
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[PMID: 22982527] |
| Fibroblast | IC50 |
21 μM
Compound: 9
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Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
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[PMID: 19788246] |
| Fibroblast | IC50 |
21 μM
Compound: A
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Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
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[PMID: 20728368] |
| Fibroblast | IC50 |
21 μM
Compound: A
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Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PA-1 | IC50 |
4.5 μM
Compound: 9
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Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
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[PMID: 19788246] |
| PA-1 | IC50 |
4.5 μM
Compound: A
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Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
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[PMID: 20728368] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PC-3 | IC50 |
9.5 μM
Compound: 9
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Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
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[PMID: 19788246] |
| PC-3 | IC50 |
9.5 μM
Compound: A
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Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
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[PMID: 20728368] |
| PC-3 | IC50 |
9.5 μM
Compound: A
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Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
Chemical Information
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CAS. Nr. 1192248-37-5
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Molecular Weight 234.25
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Formel C15H10N2O
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SMILES
O=CC1=CNC2=C1C=CC3=C2NC4=C3C=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DHPCC-9 Related Classifications
HY-115837 Related Classifications
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