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Efzofitimod

(Synonyms: ATYR-1923; KRP-R120)
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Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD).

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  • Reinheit: 99.29%
  • CAS. Nr.: 2566615-11-8
  • Molecular Weight:64.54 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Efzofitimod
  • Experimental Validation Results for Efzofitimod
  • Efzofitimod Chemical Structure
    Efzofitimod Chemical Structure
CAS. Nr.: 2566615-11-8
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Efzofitimod Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Homo sapiens HARS1 (histidyl-tRNA synthetase 1)

  • 1/16

    Immobilized Efzofitimod can bind Anti-HARS antibody. The EC50 for this effect is 36.03 ng/mL.

  • Efzofitimod Chemical Structure
    1/16
  • Efzofitimod
  • Immobilized Efzofitimod can bind Anti-HARS antibody. The EC50 for this effect is 36.03 ng/mL.
  • Homo sapiens HARS1 (histidyl-tRNA synthetase 1)